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Konstantinos Tsarouhas

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Articles 75
Citations 1309
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Recent Articles
1.
Cicek B, Danisman B, Bolat I, Kiliclioglu M, Kuzucu M, Suleyman H, et al.
J Cell Mol Med . 2024 Jul; 28(14):e18565. PMID: 39044287
Cisplatin (CIS) is a platinum-derived chemotherapeutic agent commonly utilized in the treatment of various malignant tumours. However, anticancer doses of the drug cause serious damage to the brain. This study...
2.
Cicek B, Hacimuftuoglu A, Yeni Y, Kuzucu M, Genc S, Cetin A, et al.
Environ Toxicol Pharmacol . 2024 Mar; 107:104417. PMID: 38493879
The present study was designed to evaluate whether AuNPs (gold nanoparticles) synthesized with the Cynara scolymus (CS) leaf exert protective and/or alleviative effects on arsenic (As)-induced hippocampal neurotoxicity in mice....
3.
Spanakis M, Fragkiadaki P, Renieri E, Vakonaki E, Fragkiadoulaki I, Alegakis A, et al.
Front Sports Act Living . 2024 Jan; 5:1327792. PMID: 38260814
In modern athlete assessment, the integration of conventional biochemical and ergophysiologic monitoring with innovative methods like telomere analysis, genotyping/phenotypic profiling, and metabolomics has the potential to offer a comprehensive understanding...
4.
Cicek B, Hacimuftuoglu A, Yeni Y, Danisman B, Ozkaraca M, Mokhtare B, et al.
J Pers Med . 2023 Apr; 13(4). PMID: 37109035
(1) Background: Doxorubicin (DOX) is extensively used for cancer treatments; however, its clinical application is limited because of its cardiotoxic adverse effects. A combination of DOX and agents with cardioprotective...
5.
Topal I, Ozdamar M, Catakli T, Malkoc I, Hacimuftuoglu A, Mamoulakis C, et al.
J Clin Med . 2023 Feb; 12(3). PMID: 36769524
Background: Taxifolin (TXF) is a flavonoid found abundantly in citrus/onion. Encouraging results on its renoprotective effect have been reported in a limited number of drug-induced nephrotoxicity animal models. The present...
6.
Cicek B, Genc S, Yeni Y, Kuzucu M, Cetin A, Yildirim S, et al.
J Pers Med . 2022 Dec; 12(12). PMID: 36556233
(1) Background: Various epidemiological studies suggest that oxidative stress and disrupted neuronal function are mechanistically linked to neurodegenerative diseases (NDs), including Parkinson's disease (PD) and Alzheimer's disease (AD). DNA damage,...
7.
Avci S, Gunaydin S, Ari N, Sulukoglu E, Polat O, Gecili I, et al.
J Mol Neurosci . 2022 Nov; 72(11):2292-2302. PMID: 36333611
Glutamate, one of the most important excitatory neurotransmitters, acts as a signal transducer in peripheral tissues and endocrine cells. Excessive glutamate secretion has been shown to cause excitotoxicity and neurodegenerative...
8.
Taghizadeh H, Taghizadehghalehjoughi A, Yildirim S, Ozkaraca M, Genc S, Yeni Y, et al.
J Pers Med . 2022 Oct; 12(10). PMID: 36294740
Hypertension, as a primary risk factor for many fatal disorders, is prevalent in the elderly. There is wide literature on hypertension dealing with its biological and/or biochemical aspects; however, limited...
9.
Tsarouhas K, Tsitsimpikou C, Samaras A, Saravanis C, Kolovou G, Bacopoulou F, et al.
Exp Ther Med . 2022 Oct; 24(5):699. PMID: 36277142
Long-distance running has become increasingly popular. Cardiovascular adaptations to exercise are relevant to the specific sports and this is also the case in long-distance running. Significant changes regarding inflammatory and...
10.
Georgiadis N, Tsarouhas K, Dorne J, Kass G, Laspa P, Toutouzas K, et al.
J Cardiovasc Dev Dis . 2022 Jul; 9(7). PMID: 35877588
(1) Background: Human health risks and hazards from chemical substances are well regulated internationally. However, cardiotoxicity, is not defined as a stand-alone hazard and therefore there are no defined criteria...