Konstantinos D Tsirigos
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Explore the profile of Konstantinos D Tsirigos including associated specialties, affiliations and a list of published articles.
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32
Citations
3908
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Recent Articles
1.
Sharma S, Dong Q, Haid M, Adam J, Bizzotto R, Fernandez-Tajes J, et al.
Diabetologia
. 2024 Sep;
67(12):2804-2818.
PMID: 39349772
Aims/hypothesis: Type 2 diabetes is a chronic condition that is caused by hyperglycaemia. Our aim was to characterise the metabolomics to find their association with the glycaemic spectrum and find...
2.
Eriksen R, White M, Dawed A, Perez I, Posma J, Haid M, et al.
J Clin Endocrinol Metab
. 2024 Apr;
109(9):e1697-e1707.
PMID: 38686701
Context: The role of glucagon-like peptide-1 (GLP-1) in type 2 diabetes (T2D) and obesity is not fully understood. Objective: We investigate the association of cardiometabolic, diet, and lifestyle parameters on...
3.
Brown A, Fernandez-Tajes J, Hong M, Brorsson C, Koivula R, Davtian D, et al.
Nat Commun
. 2023 Aug;
14(1):5062.
PMID: 37604891
We evaluate the shared genetic regulation of mRNA molecules, proteins and metabolites derived from whole blood from 3029 human donors. We find abundant allelic heterogeneity, where multiple variants regulate a...
4.
Roumia A, Tsirigos K, Theodoropoulou M, Tamposis I, Hamodrakas S, Bagos P
Front Bioinform
. 2022 Oct;
1:646581.
PMID: 36303794
OMPdb (www.ompdb.org) was introduced as a database for β-barrel outer membrane proteins from Gram-negative bacteria in 2011 and then included 69,354 entries classified into 85 families. The database has been...
5.
Teufel F, Almagro Armenteros J, Johansen A, Gislason M, Pihl S, Tsirigos K, et al.
Nat Biotechnol
. 2022 Jan;
40(7):1023-1025.
PMID: 34980915
Signal peptides (SPs) are short amino acid sequences that control protein secretion and translocation in all living organisms. SPs can be predicted from sequence data, but existing algorithms are unable...
6.
Quaglia F, Meszaros B, Salladini E, Hatos A, Pancsa R, Chemes L, et al.
Nucleic Acids Res
. 2021 Dec;
50(D1):D480-D487.
PMID: 34850135
The Database of Intrinsically Disordered Proteins (DisProt, URL: https://disprot.org) is the major repository of manually curated annotations of intrinsically disordered proteins and regions from the literature. We report here recent...
7.
Tamposis I, Sarantopoulou D, Theodoropoulou M, Stasi E, Kontou P, Tsirigos K, et al.
Comput Struct Biotechnol J
. 2021 Dec;
19:6090-6097.
PMID: 34849210
Hidden Markov Models (HMMs) are amongst the most successful methods for predicting protein features in biological sequence analysis. However, there are biological problems where the Markovian assumption is not sufficient...
8.
Tura A, Grespan E, Gobl C, Koivula R, Franks P, Pearson E, et al.
Diabetes
. 2021 Jul;
70(9):2092-2106.
PMID: 34233929
Differences in glucose metabolism among categories of prediabetes have not been systematically investigated. In this longitudinal study, participants ( = 2,111) underwent a 2-h 75-g oral glucose tolerance test (OGTT)...
9.
Bizzotto R, Jennison C, Jones A, Kurbasic A, Tura A, Kennedy G, et al.
Diabetes Care
. 2020 Dec;
44(2):511-518.
PMID: 33323478
Objective: We investigated the processes underlying glycemic deterioration in type 2 diabetes (T2D). Research Design And Methods: A total of 732 recently diagnosed patients with T2D from the Innovative Medicines...
10.
Eriksen R, Perez I, Posma J, Haid M, Sharma S, Thomas L, et al.
EBioMedicine
. 2020 Aug;
58:102932.
PMID: 32763829
Background: Dietary advice remains the cornerstone of prevention and management of type 2 diabetes (T2D). However, understanding the efficacy of dietary interventions is confounded by the challenges inherent in assessing...