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Konrad Trulzsch

Explore the profile of Konrad Trulzsch including associated specialties, affiliations and a list of published articles. Areas
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Articles 28
Citations 650
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Recent Articles
1.
Wolters M, Boyle E, Lardong K, Trulzsch K, Steffen A, Rottner K, et al.
J Biol Chem . 2013 Jun; 288(32):23543-53. PMID: 23803609
Pathogenic Yersinia spp. translocate the effectors YopT, YopE, and YopO/YpkA into target cells to inactivate Rho family GTP-binding proteins and block immune responses. Some Yersinia spp. also secrete the Rho...
2.
Trcek J, Oellerich M, Niedung K, Ebel F, Freund S, Trulzsch K
BMC Res Notes . 2011 Apr; 4:129. PMID: 21501502
Background: Yersinia enterocolitica is a common cause of food borne gastrointestinal disease. After oral uptake, yersiniae invade Peyer's patches of the distal ileum. This is accomplished by the binding of...
3.
Schneider M, Dahlhoff M, Horst D, Hirschi B, Trulzsch K, Muller-Hocker J, et al.
PLoS One . 2010 Dec; 5(12):e14325. PMID: 21179475
Background: E-cadherin is a major component of adherens junctions. Impaired expression of E-cadherin in the small intestine and colon has been linked to a disturbed intestinal homeostasis and barrier function....
4.
Gaus K, Hentschke M, Czymmeck N, Novikova L, Trulzsch K, Valentin-Weigand P, et al.
Infect Immun . 2010 Dec; 79(3):1166-75. PMID: 21149597
Pathogenic Yersinia species inject a panel of Yop virulence proteins by type III protein secretion into host cells to modulate cellular defense responses. This enables the survival and dissemination of...
5.
Trcek J, Berschl K, Trulzsch K
FEMS Microbiol Lett . 2010 Jul; 307(2):201-6. PMID: 20636977
Yersiniae expressing an L-arabinose-inducible luxCDABE reporter were used to analyze the colonization of mice. Infection of live mice was followed over a period of 6 days. These experiments revealed frequent...
6.
Trcek J, Fuchs T, Trulzsch K
Microbiology (Reading) . 2010 Jun; 156(Pt 9):2734-2745. PMID: 20558509
A novel luxCDABE plasmid for the analysis of promoter elements by site-specific integration into the genome of Yersinia enterocolitica was constructed. The versatility of this reporter system was demonstrated by...
7.
Deuretzbacher A, Czymmeck N, Reimer R, Trulzsch K, Gaus K, Hohenberg H, et al.
J Immunol . 2009 Oct; 183(9):5847-60. PMID: 19812190
Autophagy is a central lysosomal degradation process that is essential for the maintenance of cellular homeostasis. Autophagy has furthermore emerged as integral part of the host immune response. Autophagic processes...
8.
Schmid A, Neumayer W, Trulzsch K, Israel L, Imhof A, Roessle M, et al.
J Biol Chem . 2009 Feb; 284(18):12165-77. PMID: 19244229
Pathogenic yersiniae utilize a type three secretion system (T3SS) to inject Yop proteins into host cells in order to undermine their immune response. YscM1 and YscM2 proteins have been reported...
9.
Leibiger R, Niedung K, Geginat G, Heesemann J, Trulzsch K
Vaccine . 2008 Sep; 26(51):6664-70. PMID: 18822332
Attenuated enteropathogenic yersiniae that translocate heterologous antigens into the cytosol of antigen presenting cells via their type three secretion system (TTSS) are considered promising candidates for the development of live...
10.
Freund S, Czech B, Trulzsch K, Ackermann N, Heesemann J
J Bacteriol . 2008 Apr; 190(12):4111-20. PMID: 18408033
As a first approach to establishing a three-dimensional culture infection model, we studied the growth behavior of the extracellular pathogen Yersinia enterocolitica in three-dimensional collagen gels (3D-CoG). Surprisingly, we observed...