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Kole R DeGolier

Explore the profile of Kole R DeGolier including associated specialties, affiliations and a list of published articles. Areas
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Recent Articles
1.
DeGolier K, Danis E, DAntonio M, Cimons J, Yarnell M, Kedl R, et al.
Nat Immunol . 2025 Jan; 26(1):68-81. PMID: 39747430
Although chimeric antigen receptor (CAR) T cells are effective against B-lineage malignancies, post-CAR relapse is common, and efficacy in other tumors is limited. These challenges may be addressed through rational...
2.
DeGolier K, Danis E, DAntonio M, Cimons J, Yarnell M, Kedl R, et al.
Res Sq . 2024 Jan; PMID: 38196657
Chimeric antigen receptor T cells are an effective therapy for B-lineage malignancies. However, many patients relapse and this therapeutic has yet to show strong efficacy in other hematologic or solid...
3.
Gardell J, Matsumoto L, Chinn H, DeGolier K, Kreuser S, Prieskorn B, et al.
J Immunother Cancer . 2020 Oct; 8(2). PMID: 33122397
Background: Targeted and effective treatment options are needed for solid tumors, including glioblastoma (GBM), where survival rates with standard treatments are typically less than 2 years from diagnosis. Solid tumors...
4.
Brempelis K, Cowan C, Kreuser S, Labadie K, Prieskorn B, Lieberman N, et al.
J Immunother Cancer . 2020 Oct; 8(2). PMID: 33115946
Background: Though currently approved immunotherapies, including chimeric antigen receptor T cells and checkpoint blockade antibodies, have been successfully used to treat hematological and some solid tumor cancers, many solid tumors...