Koji Itahana
Overview
Explore the profile of Koji Itahana including associated specialties, affiliations and a list of published articles.
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Articles
48
Citations
5059
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Recent Articles
11.
Tumor Suppressor p14ARF Enhances IFN-γ-Activated Immune Response by Inhibiting PIAS1 via SUMOylation
Alagu J, Itahana Y, Sim F, Chao S, Bi X, Itahana K
J Immunol
. 2018 Jun;
201(2):451-464.
PMID: 29848755
The ability of cells to induce the appropriate transcriptional response to inflammatory stimuli is crucial for the timely induction of host defense mechanisms. Although a role for tumor suppressor p14ARF...
12.
Itahana Y, Itahana K
Int J Mol Sci
. 2018 Mar;
19(3).
PMID: 29518025
Glucose is the key source for most organisms to provide energy, as well as the key source for metabolites to generate building blocks in cells. The deregulation of glucose homeostasis...
13.
Liu Y, Leslie P, Jin A, Itahana K, Graves L, Zhang Y
FASEB J
. 2018 Feb;
32(7):3892-3902.
PMID: 29465311
Sustained endoplasmic reticulum (ER) stress plays a major role in the development of many metabolic diseases, including cardiovascular disease, nonalcoholic fatty liver disease, insulin resistance, obesity, and diabetes. p32 is...
14.
Lee H, Itahana Y, Schuechner S, Fukuda M, Je H, Ogris E, et al.
Sci Signal
. 2018 Jan;
11(512).
PMID: 29317521
Cancer cells increase glucose metabolism to support aerobic glycolysis. However, only some cancer cells are acutely sensitive to glucose withdrawal, and the underlying mechanism of this selective sensitivity is unclear....
15.
Chan S, Lim W, Michalski S, Lim J, Ishak N, Met-Domestici M, et al.
NPJ Genom Med
. 2017 Dec;
1:16015.
PMID: 29263814
Li-Fraumeni syndrome (LFS) is a rare cancer predisposition syndrome usually associated with germline alterations. Its genetic basis in wild-type pedigrees is less understood. Using whole-genome sequencing, we identified a germline...
16.
Liu Y, Leslie P, Jin A, Itahana K, Graves L, Zhang Y
Sci Rep
. 2017 Jul;
7(1):5754.
PMID: 28720899
Obesity is increasing in prevalence and has become a global public health problem. The main cause of obesity is a perturbation in energy homeostasis, whereby energy intake exceeds energy expenditure....
17.
Baskar R, Itahana K
Int J Med Sci
. 2017 Feb;
14(1):13-17.
PMID: 28138304
Globally, morbidity and mortality due to cancer are predicted to increase in both men and women in the coming decades. Furthermore, it is estimated that two thirds of these cancer-related...
18.
Itahana Y, Zhang J, Goke J, Vardy L, Han R, Iwamoto K, et al.
Sci Rep
. 2016 Jun;
6:28112.
PMID: 27346849
The high proliferation rate of embryonic stem cells (ESCs) is thought to arise partly from very low expression of p21. However, how p21 is suppressed in ESCs has been unclear....
19.
Yeo S, Itahana Y, Guo A, Han R, Iwamoto K, Nguyen H, et al.
Elife
. 2016 Mar;
5:e07101.
PMID: 26956429
Genetic alterations which impair the function of the TP53 signaling pathway in TP53 wild-type human tumors remain elusive. To identify new components of this pathway, we performed a screen for...
20.
Klionsky D, Abdelmohsen K, Abe A, Abedin M, Abeliovich H, Arozena A, et al.
Autophagy
. 2016 Jan;
12(1):1-222.
PMID: 26799652
No abstract available.