Koji Itahana
Overview
Explore the profile of Koji Itahana including associated specialties, affiliations and a list of published articles.
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Articles
48
Citations
5059
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Recent Articles
1.
Mariya Vincent D, Mostafa H, Suneer A, Radha Krishnan S, Ong M, Itahana Y, et al.
Chemistry
. 2024 Aug;
30(63):e202401782.
PMID: 39190779
The emergence of drug resistance in cancer cells eventually causing relapse is a serious threat that demands new advances. Upregulation of the ATP-dependent binding cassette (ABC) transporters, such as ABCB1,...
2.
Jagannathan N, Koh J, Lee Y, Sobota R, Irving A, Wang L, et al.
Elife
. 2024 Jul;
13.
PMID: 39037770
Bats have unique characteristics compared to other mammals, including increased longevity and higher resistance to cancer and infectious disease. While previous studies have analyzed the metabolic requirements for flight, it...
3.
Koh J, Itahana Y, Krah A, Mostafa H, Ong M, Iwamura S, et al.
Commun Chem
. 2024 Jul;
7(1):158.
PMID: 39003409
Chemotherapy-induced drug resistance remains a major cause of cancer recurrence and patient mortality. ATP binding cassette subfamily B member 1 (ABCB1) transporter overexpression in tumors contributes to resistance, yet current...
4.
Ohki R, Itahana K, Iwakuma T
Genes Cells
. 2024 Mar;
29(6):451-455.
PMID: 38553254
The 10th International MDM2 Workshop was held at the National Cancer Center Research Institute (NCCRI) in Tokyo, Japan, from October 15 to 18, 2023. It attracted 166 participants from 12...
5.
Bischof O, Kirsh O, Pearson M, Itahana K, Pelicci P, Dejean A
EMBO J
. 2022 Sep;
41(17):e112081.
PMID: 36047049
No abstract available.
6.
Lee Y, Itahana Y, Ong C, Itahana K
J Cell Sci
. 2022 Jul;
135(15).
PMID: 35775474
Accelerated aerobic glycolysis is a distinctive metabolic property of cancer cells that confers dependency on glucose for survival. However, the therapeutic strategies targeting this vulnerability are still inefficient and have...
7.
Guo A, Itahana Y, Seshachalam V, Chow H, Ghosh S, Itahana K
Br J Cancer
. 2020 Nov;
124(1):299-312.
PMID: 33144694
Background: Mutant TP53 interacts with other proteins to produce gain-of-function properties that contribute to cancer metastasis. However, the underlying mechanisms are still not fully understood. Methods: Using immunoprecipitation and proximity...
8.
Sun A, Yuan Q, Fukuda M, Yu W, Yan H, Lim G, et al.
Science
. 2019 Dec;
366(6472):1486-1492.
PMID: 31857479
Disruptions in the ubiquitin protein ligase E3A () gene cause Angelman syndrome (AS). Whereas AS model mice have associated synaptic dysfunction and altered plasticity with abnormal behavior, whether similar or...
9.
Koh J, Itahana Y, Mendenhall I, Low D, Soh E, Guo A, et al.
Nat Commun
. 2019 Jun;
10(1):2820.
PMID: 31249297
Bats are unusual mammals, with the ability to fly, and long lifespans. In addition, bats have a low incidence of cancer, but the mechanisms underlying this phenomenon remain elusive. Here...
10.
Chionh Y, Cui J, Koh J, Mendenhall I, Ng J, Low D, et al.
Cell Stress Chaperones
. 2019 Jun;
24(4):835-849.
PMID: 31230214
Bats, unique among mammals with powered flight, have many species with the longest size-proportionate lifespan of all mammals. Evolutionary adaptations would have been required to survive the elevated body temperatures...