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Koichi Takagi

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Articles 38
Citations 276
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Recent Articles
1.
Hamu-Tanoue A, Takagi K, Taketomi Y, Miki Y, Nishito Y, Kano K, et al.
FASEB J . 2024 Jan; 38(2):e23428. PMID: 38236184
Asthma is a chronic inflammatory disease of the airways characterized by recurrent episodes of airway obstruction, hyperresponsiveness, remodeling, and eosinophilia. Phospholipase A s (PLA s), which release fatty acids and...
2.
Matsuyama T, Machida K, Mizuno K, Matsuyama H, Dotake Y, Shinmura M, et al.
Biomolecules . 2023 Jun; 13(6). PMID: 37371472
Asthma is a heterogeneous disease characterized by chronic airway inflammation. Group 2 innate lymphoid cells (ILC2) play an important role in the pathogenesis of asthma. ILC2s lack antigen-specific receptors and...
3.
Takahashi K, Kawayama T, Takamori A, Tashiro H, Kinoshita T, Takagi K, et al.
BMJ Open Respir Res . 2023 May; 10(1). PMID: 37197795
Introduction: Bronchodilators, including long-acting muscarinic antagonists (LAMA) and long-acting beta 2 agonists (LABA), are the main treatments for chronic obstructive pulmonary disease (COPD). The efficacy of triple therapy (inhaled corticosteroids/LAMA/LABA)...
4.
Matsuyama T, Tomioka Y, Matsuyama H, Kamenohara Y, Tanigawa K, Dotake Y, et al.
Respirol Case Rep . 2023 May; 11(6):e01158. PMID: 37180095
Mepolizumab, a humanized anti-IL-5 monoclonal antibody used for severe asthma, results in a reduced rate of asthma exacerbation, improved lung function, reduced oral corticosteroid use, and improved quality of life....
5.
Yamamoto K, Ikeya T, Kanomata N, Deshpande G, Takagi K, Omata F
Case Rep Gastroenterol . 2022 Aug; 16(2):368-374. PMID: 35949242
Gastric subepithelial lesions (SEL) are usually found incidentally during esophagogastroduodenoscopy. Most gastric SELs are benign lesions, such as leiomyoma and pancreatic rests. However, neoplastic lesions including neuroendocrine tumors, gastrointestinal stromal...
6.
Matsuyama T, Matsuyama H, Dotake Y, Takagi K, Machida K, Inoue H
Front Immunol . 2022 Aug; 13:930862. PMID: 35911708
T helper type 2 cells (Th2 cells) and group 2 innate lymphoid cells (ILC2s) play an important role in the pathophysiology of asthma, including airway eosinophilic inflammation. ILC2s are activated...
7.
Matsuyama T, Machida K, Hamu A, Takagi K, Momi H, Higashimoto I, et al.
Respir Investig . 2022 Jun; 60(5):633-639. PMID: 35659856
Background: Inhaled medication is the cornerstone of pharmacological treatment for asthma. Poor inhaler techniques are associated with poor asthma control and an increased risk of exacerbations. Leaflets and videos are...
8.
Kondo K, Harada Y, Nakano M, Suzuki T, Fukushige T, Hanzawa K, et al.
J Biol Chem . 2022 Apr; 298(6):101950. PMID: 35447118
Asparagine-linked glycosylation (N-glycosylation) of proteins in the cancer secretome has been gaining increasing attention as a potential biomarker for cancer detection and diagnosis. Small extracellular vesicles (sEVs) constitute a large...
9.
Okamoto T, Yamamoto K, Takasu A, Suzuki Y, Ikeya T, Okuyama S, et al.
JGH Open . 2022 Mar; 6(3):179-184. PMID: 35355672
Aims: Studies detailing endoscopic findings and hemostatic interventions for upper gastrointestinal bleeding after cardiovascular surgery are scarce. We conducted this study to determine the frequency and findings of emergent esophagogastroduodenoscopy...
10.
Takasu A, Ikeya T, Shiratori Y, Dai Z, Yoshimoto T, Yamamoto K, et al.
Intern Med . 2022 Mar; 61(20):3009-3016. PMID: 35314553
Objective A high NOBLADS score reflecting the severity of lower gastrointestinal bleeding contributes to the identification of stigmata of recent hemorrhage (SRH) in colonic diverticular bleeding (CDB). The burden of...