Koichi Shudo
Overview
Explore the profile of Koichi Shudo including associated specialties, affiliations and a list of published articles.
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Articles
73
Citations
724
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Recent Articles
1.
Tamura K, Hashimoto Y, Shudo K, Ide H
Dev Growth Differ
. 2023 Jun;
35(5):593-599.
PMID: 37281673
An autoradiographic analysis was undertaken to examine the localization of retinoids applied exogenously to chick limb buds. Ion-exchange beads (AGI-X2) containing a tritium-labeled synthetic retinoid, Am80, were implanted to various...
2.
Tsuji M, Shudo K, Kagechika H
FEBS Open Bio
. 2017 Mar;
7(3):391-396.
PMID: 28286734
Understanding and identifying the receptor subtype selectivity of a ligand is an important issue in the field of drug discovery. Using a combination of classical molecular mechanics and quantum mechanical...
3.
Oya Y, Mondal A, Rawangkan A, Umsumarng S, Iida K, Watanabe T, et al.
J Nutr Biochem
. 2017 Jan;
42:7-16.
PMID: 28103535
(-)-Epigallocatechin gallate (EGCG), a green tea catechin, acts as a synergist with various anticancer drugs, including retinoids. Am80 is a synthetic retinoid with a different structure from all-trans-retinoic acid: Am80...
4.
Li L, Qi X, Sun W, Abdel-Azim H, Lou S, Zhu H, et al.
EMBO Mol Med
. 2016 Oct;
8(11):1340-1359.
PMID: 27737899
Neutrophils generated by granulocyte colony-stimulating factor (GCSF) are functionally immature and, consequently, cannot effectively reduce infection and infection-related mortality in cancer chemotherapy-induced neutropenia (CCIN). Am80, a retinoic acid (RA) agonist...
5.
Dulla Y, Kurauchi Y, Hisatsune A, Seki T, Shudo K, Katsuki H
Neurochem Res
. 2016 Jul;
41(11):2848-2858.
PMID: 27401255
Inhibition of pro-inflammatory functions of microglia has been considered a promising strategy to prevent pathogenic events in the central nervous system under neurodegenerative conditions. Here we examined potential inhibitory effects...
6.
Takaoka Y, Takahashi M, Kurauchi Y, Hisatsune A, Seki T, Shudo K, et al.
Int Immunopharmacol
. 2016 Jun;
38:367-76.
PMID: 27351827
Accumulating lines of evidence suggest that retinoic acid receptor agonists such as Am80 exerts anti-inflammatory actions in the central nervous system, although detailed mechanisms of the action remain largely unknown....
7.
Reinhardt S, Grimm M, Stahlmann C, Hartmann T, Shudo K, Tomita T, et al.
Curr Alzheimer Res
. 2016 Jun;
13(11):1277-1289.
PMID: 27335034
Retinoic acid, the bioactive metabolite of beta-carotene or vitamin A, plays a pleiotropic, multifunctional role in vertebrate development. Studies in rodents revealed that a diet deficient in vitamin A results...
8.
Toyama T, Asano Y, Akamata K, Noda S, Taniguchi T, Takahashi T, et al.
J Invest Dermatol
. 2016 Mar;
136(2):387-398.
PMID: 26967475
Tamibarotene (Am80) is a synthetic retinoid that modulates the pathologic processes of various autoimmune and inflammatory diseases and their animal models. We here investigated the therapeutic potential of Am80 against...
9.
Fujibayashi T, Kurauchi Y, Hisatsune A, Seki T, Shudo K, Katsuki H
J Pharmacol Sci
. 2015 Oct;
129(2):119-26.
PMID: 26422672
We have previously shown that retinoic acid receptor (RAR) stimulation by an agonist Am80 recruits nitric oxide-dependent signaling via increased expression of neuronal nitric oxide synthase (nNOS) in rat midbrain...
10.
Tsuji M, Shudo K, Kagechika H
J Comput Aided Mol Des
. 2015 Sep;
29(10):975-88.
PMID: 26384496
Retinoid X receptors (RXRs) are ligand-controlled transcription factors which heterodimerize with other nuclear receptors to regulate gene transcriptions associated with crucial biological events. 9-cis retinoic acid (9cRA), which transactivates RXRs,...