Koichi Sakakura
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Explore the profile of Koichi Sakakura including associated specialties, affiliations and a list of published articles.
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48
Citations
3899
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Recent Articles
11.
Motokawa Y, Kokubo M, Kuwabara N, Tatematsu K, Sezutsu H, Takahashi H, et al.
Exp Ther Med
. 2018 Mar;
15(3):2512-2518.
PMID: 29563979
Recent clinical trials with the aim of developing tumor antigen (TA)-specific cancer vaccines against a number of malignancies have focused on the identification of TAs presented by tumor cells and...
12.
Kawada T, Takahashi H, Sakakura K, Ida S, Mito I, Toyoda M, et al.
Head Neck
. 2017 Aug;
39(11):2180-2186.
PMID: 28815839
Background: The purpose of this study was to present our findings that because circulating tumor cells (CTCs) exist in extremely low numbers, their detection and quantification are challenging. Methods: Peripheral...
13.
Takahashi H, Sakakura K, Kudo T, Toyoda M, Kaira K, Oyama T, et al.
Oncotarget
. 2017 Jan;
8(5):8633-8647.
PMID: 28052009
Stromal cells in the tumor microenvironment (TME) closely interact with tumor cells and affect tumor cell behavior in diverse manners. We herein investigated the mechanisms by which cancer-associated fibroblasts (CAFs)...
14.
Sakakura K, Tazawa M, Otani N, Takagi M, Morita M, Kurosaki M, et al.
Ann Otol Rhinol Laryngol
. 2016 Dec;
126(1):47-53.
PMID: 27913722
Objectives: The management of dysphagia requires a multidisciplinary approach, especially in large-scale hospitals. We introduce a novel protocol using a Wi-Fi-based flexible endoscopic evaluation of swallowing (FEES) system and aim...
15.
Sakakura K, Takahashi H, Kaira K, Toyoda M, Murata T, Ohnishi H, et al.
Lab Invest
. 2016 Jun;
96(9):994-1003.
PMID: 27322955
Tumor-associated macrophages (TAM) have been classified into an immunostimulatory M1 subset against microbes and malignancies, and an immunoregulatory M2 subset that secretes immunosuppressive cytokines in order to repair tissues damaged...
16.
Kaira K, Toyoda M, Shimizu A, Imai H, Sakakura K, Nikkuni O, et al.
Head Neck
. 2016 Jun;
38(10):1539-44.
PMID: 27312568
Background: The immunoglobulin heavy chain binding protein (BiP)/glucose-regulated protein 78 (GRP78) is important in the endoplasmic reticulum stress, and is highly expressed in various human cancers. The clinical and pathological...
17.
Takahashi H, Sakakura K, Mito I, Ida S, Chikamatsu K
Cancer Sci
. 2016 May;
107(8):1065-71.
PMID: 27228557
Tumor cells have evolved sophisticated means of escape from the host immune system. To date, several important immunological phenomena have been revealed in peripheral blood as well as within tumors....
18.
Klionsky D, Abdelmohsen K, Abe A, Abedin M, Abeliovich H, Arozena A, et al.
Autophagy
. 2016 Jan;
12(1):1-222.
PMID: 26799652
No abstract available.
19.
Kaira K, Toyoda M, Shimizu A, Shino M, Sakakura K, Takayasu Y, et al.
Acta Otolaryngol
. 2015 Sep;
136(1):1-7.
PMID: 26366837
Conclusion: A high GRP78/BiP expression was proved to be a significant marker for predicting poor outcome after surgery. GRP78/BiP may be a promising molecular target for treatment of ACC. Background:...
20.
Immunosuppressive activity of cancer-associated fibroblasts in head and neck squamous cell carcinoma
Takahashi H, Sakakura K, Kawabata-Iwakawa R, Rokudai S, Toyoda M, Nishiyama M, et al.
Cancer Immunol Immunother
. 2015 Jul;
64(11):1407-17.
PMID: 26201938
Cancer-associated fibroblasts (CAFs) have been shown to play an important role in angiogenesis, invasion, and metastasis. In the present study, we determined whether CAFs within the tumor microenvironment (TME) in...