Koho Iizuka
Overview
Explore the profile of Koho Iizuka including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
13
Citations
942
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Adams S, Diamond J, Hamilton E, Pohlmann P, Tolaney S, Chang C, et al.
JAMA Oncol
. 2018 Oct;
5(3):334-342.
PMID: 30347025
Importance: The humanized monoclonal antibody atezolizumab targets programmed death-ligand 1 and has demonstrated durable single-agent activity in a subset of metastatic triple-negative breast cancers. To extend the observed activity, combinatorial...
2.
Liu S, Camidge D, Gettinger S, Giaccone G, Heist R, Hodi F, et al.
Eur J Cancer
. 2018 Jul;
101:114-122.
PMID: 30053670
Background: Before the availability of immunotherapy, chemotherapy was standard first-line therapy for non-small-cell lung cancer (NSCLC) lacking actionable gene alterations. Preclinical evidence suggests chemotherapy is immunomodulatory, supporting chemotherapy/immunotherapy combinations. Atezolizumab,...
3.
Suzuki K, Ogura M, Abe Y, Suzuki T, Tobinai K, Ando K, et al.
Int J Hematol
. 2015 Feb;
101(3):286-94.
PMID: 25655379
Siltuximab, a chimeric monoclonal antibody with high affinity and specificity for interleukin-6, has been shown to enhance anti-multiple myeloma activity of bortezomib and corticosteroid in vitro. We evaluated the safety,...
4.
Matsubara N, Uemura H, Fukui I, Niwakawa M, Yamaguchi A, Iizuka K, et al.
Cancer Sci
. 2014 Aug;
105(10):1313-20.
PMID: 25117615
Persistent androgen synthesis under castration status in adrenal gland, testes and tumor cells is thought to be one of the major causes of development and progression of castration-resistant prostate cancer...
5.
Iizuka Y, Somia N, Iizuka K
Methods Mol Biol
. 2009 Dec;
612:285-97.
PMID: 20033648
NK cell responses are regulated by a balance of inhibitory and activating signals, reflecting the net effect of interactions between receptors and ligands on target and effector cell surfaces. The...
6.
Ito D, Iizuka Y, Katepalli M, Iizuka K
Proc Natl Acad Sci U S A
. 2009 Jun;
106(27):11264-9.
PMID: 19549850
NK cells use surface NK receptors to discriminate self from non-self. The NK receptor ligand-binding domain (NKD) has been considered the sole regulator of ligand binding. Using a prototypic murine...
7.
Iizuka K, Scalzo A, Xian H, Yokoyama W
J Immunol
. 2008 Feb;
180(5):3260-7.
PMID: 18292550
Host NK cells can reject MHC-incompatible (allogeneic) bone marrow cells (BMCs), suggesting their effective role for graft-vs leukemia effects in the clinical setting of bone marrow transplantation. NK cell-mediated rejection...
8.
Iizuka K, Nakajima C, Iizuka Y, Takase M, Kato T, Noda S, et al.
J Immunol
. 2007 Jul;
179(2):1122-8.
PMID: 17617605
CMV infection is one of the most common complications in immunocompromised individuals, such as organ and bone marrow transplant patients. Both innate and adaptive immune responses are required for defense...
9.
Kim S, Song Y, Higuchi D, Kang H, Pratt J, Yang L, et al.
Blood
. 2005 Oct;
107(3):1024-30.
PMID: 16223777
Natural killer (NK) cell development in the bone marrow is not fully understood. Following lineage commitment, these cells appear to advance through a series of developmental stages that are beginning...
10.
Iizuka K, Naidenko O, Plougastel B, Fremont D, Yokoyama W
Nat Immunol
. 2003 Jul;
4(8):801-7.
PMID: 12858173
The natural killer (NK) gene complex (NKC) encodes orphan lectin-like NK cell receptors that may explain uncharacterized NK cell specificities. Unlike other NKC-encoded receptors that recognize molecules with major histocompatibility...