Koh Takeuchi
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Explore the profile of Koh Takeuchi including associated specialties, affiliations and a list of published articles.
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132
Citations
1893
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Recent Articles
1.
Takeuchi K, Nagase L, Kageyama S, Kanoh H, Oshima M, Ogawa-Iio A, et al.
FEBS J
. 2025 Jan;
PMID: 39828902
Phosphatidylinositol 5-phosphate 4-kinases (PI5P4K), also known as type II PIPKs or PIPKIIs, convert the lipid second messenger PI5P to PI(4,5)P. The PI5P4K family consists of three isozymes in mammals-PI5P4Kα, β,...
2.
Shimano R, Takeuchi K, Komatsu T, Inamura J, Miyazaki S, Akita M
J Surg Case Rep
. 2024 Dec;
2024(12):rjae792.
PMID: 39697277
Rupture of abdominal aortic aneurysm (AAA) due to an isolated type II endoleak (TIIEL) is rarely reported, accounting for less than 1% of all TIIELs; typically, rupture associated with TIIEL...
3.
Yanagi T, Kikuchi H, Takeuchi K, Susa K, Mori T, Chiga M, et al.
Kidney Int
. 2024 Oct;
106(5):887-906.
PMID: 39428173
Adenosine monophosphate (AMP)-activated protein kinase (AMPK) is a central kinase involved in energy homeostasis. Increased intracellular AMP levels result in AMPK activation through the binding of AMP to the γ-subunit...
4.
Otani Y, Ichinose A, Wang X, Huang Z, Kasahara A, Ishii M, et al.
Chem Commun (Camb)
. 2024 Aug;
60(69):9242-9245.
PMID: 39115107
We designed and synthesized an -nitrobenzylated benzanilide-based amino acid having a -amide structure that facilitates cyclization of peptides containing it. Photo-induced removal of the nitrobenzyl group from this residue in...
5.
Takeuchi K, Ueda T, Imai M, Fujisaki M, Shimura M, Tokunaga Y, et al.
Structure
. 2024 May;
32(8):1150-1164.e3.
PMID: 38815577
Multidrug and toxin extrusion (MATE) family transporters excrete toxic compounds coupled to Na/H influx. Although structures of MATE transporters are available, the mechanism by which substrate export is coupled to...
6.
Yokomine M, Morimoto J, Fukuda Y, Ueda T, Takeuchi K, Umezawa K, et al.
Chem Sci
. 2024 May;
15(19):7051-7060.
PMID: 38756815
Peptoids are a promising drug modality targeting disease-related proteins, but how a peptoid engages in protein binding is poorly understood. This is primarily due to a lack of high-resolution peptoid-protein...
7.
Nishimura T, Kudo K, Izumikawa M, Kozone I, Hashimoto J, Kagaya N, et al.
Chem Pharm Bull (Tokyo)
. 2024 May;
72(5):475-479.
PMID: 38749722
Heterologous expression of natural compound biosynthetic gene clusters (BGCs) is a robust approach for not only revealing the biosynthetic mechanisms leading to the compounds, but also for discovering new products...
8.
Kofuji S, Wolfe K, Sumita K, Kageyama S, Yoshino H, Hirota Y, et al.
Biochem Biophys Res Commun
. 2024 May;
718:149981.
PMID: 38735134
In animal cells, vacuoles are absent, but can be induced by diseases and drugs. While phosphoinositides are critical for membrane trafficking, their role in the formation of these vacuoles remains...
9.
Takeda Y, Chinen T, Honda S, Takatori S, Okuda S, Yamamoto S, et al.
Nat Commun
. 2024 Mar;
15(1):2216.
PMID: 38519454
The triplet microtubule, a core structure of centrioles crucial for the organization of centrosomes, cilia, and flagella, consists of unclosed incomplete microtubules. The mechanisms of its assembly represent a fundamental...
10.
Fujii K, Takeuchi K, Kuribayashi A, Takeishi N, Kawahara Y, Takeda K
IEEE Trans Neural Netw Learn Syst
. 2024 Feb;
36(2):2103-2117.
PMID: 38408010
Evaluation of intervention in a multiagent system, for example, when humans should intervene in autonomous driving systems and when a player should pass to teammates for a good shot, is...