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Kobi Rosenblum

Explore the profile of Kobi Rosenblum including associated specialties, affiliations and a list of published articles. Areas
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Articles 84
Citations 2620
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Recent Articles
1.
Izkovich B, Yiannakas A, Neeman S, Chandran S, Rosenblum K, Edry E
Mol Brain . 2025 Mar; 18(1):19. PMID: 40087800
Peptide drug technologies offer powerful approaches to develop potent and selective lead molecules for therapeutic and research applications. However, new and optimized delivery approaches are necessary to overcome current pitfalls...
2.
Kayyal H, Cruciani F, Chandran S, Edry E, Schif-Zuck S, Koren T, et al.
Nat Neurosci . 2025 Jan; 28(3):589-601. PMID: 39870921
To protect the body from infections, the brain has evolved the ability to coordinate behavioral and immunological responses. The conditioned immune response (CIR) is a form of Pavlovian conditioning wherein...
3.
Ruggiero A, Heim L, Susman L, Hreaky D, Shapira I, Katsenelson M, et al.
Neuron . 2024 Nov; 113(2):244-259.e7. PMID: 39515323
Understanding how neuronal circuits stabilize their activity is a fundamental yet poorly understood aspect of neuroscience. Here, we show that hippocampal network properties, such as firing rate distribution and dimensionality,...
4.
Sharma V, Oliveira M, Sood R, Khlaifia A, Lou D, Hooshmandi M, et al.
Proc Natl Acad Sci U S A . 2023 Nov; 120(49):e2308671120. PMID: 38015848
Activation of neuronal protein synthesis upon learning is critical for the formation of long-term memory. Here, we report that learning in the contextual fear conditioning paradigm engenders a decrease in...
5.
Gould N, Scherer G, Carvalho S, Shurrush K, Kayyal H, Edry E, et al.
J Clin Invest . 2023 Aug; 133(19). PMID: 37561584
Biological aging can be described as accumulative, prolonged metabolic stress and is the major risk factor for cognitive decline and Alzheimer's disease (AD). Recently, we identified and described a quinone...
6.
Mekiten O, Yitzhaky A, Gould N, Rosenblum K, Hertzberg L
J Psychiatr Res . 2023 Jul; 164:372-381. PMID: 37413782
One of the new theories accounting for the underlying pathophysiology of schizophrenia is excitation/inhibition imbalance. Interestingly, perturbation in protein synthesis machinery as well as oxidative stress can lead to excitation/inhibition...
7.
Storkebaum E, Rosenblum K, Sonenberg N
N Engl J Med . 2023 May; 388(22):2110-2111. PMID: 37256994
No abstract available.
8.
Storkebaum E, Rosenblum K, Sonenberg N
N Engl J Med . 2023 Mar; 388(11):1015-1030. PMID: 36920757
No abstract available.
9.
Chandran S, Yiannakas A, Kayyal H, Salalha R, Cruciani F, Mizrahi L, et al.
eNeuro . 2023 Jan; 10(1). PMID: 36635250
Avoiding potentially harmful, and consuming safe food is crucial for the survival of living organisms. However, the perceived valence of sensory information can change following conflicting experiences. Pleasurability and aversiveness...
10.
Beiser T, Lisniansky E, Weitz M, Bingor A, Grad E, Rosenblum K, et al.
Transl Psychiatry . 2022 Nov; 12(1):460. PMID: 36319619
Recent evidence links synaptic plasticity and mRNA translation, via the eukaryotic elongation factor 2 kinase (eEF2K) and its only known substrate, eEF2. However, the involvement of the eEF2 pathway in...