Kiyoshi Yamaguchi
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Explore the profile of Kiyoshi Yamaguchi including associated specialties, affiliations and a list of published articles.
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Articles
117
Citations
1770
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Recent Articles
1.
Kuse Y, Matsumoto S, Tsuzuki S, Carolina E, Okumura T, Kasai T, et al.
Nat Commun
. 2025 Mar;
16(1):2493.
PMID: 40082402
Organoids derived from human induced pluripotent stem cells (hiPSC) are potentially applicable for regenerative medicine. However, the applications have been hampered by limited organoid size and function as a consequence...
2.
Ito G, Ota Y, Yamaguchi K, Furukawa Y, Mochizuki S, Ahiko Y, et al.
World J Surg Oncol
. 2025 Feb;
23(1):57.
PMID: 39966961
Background: With recent advances in genetics research, genetic analysis is increasingly being used in clinical practice. We report a case in which genetic analysis aided in diagnosing a local recurrence...
3.
Sato R, Liu K, Shibata T, Hoshino K, Yamaguchi K, Miyazaki T, et al.
J Exp Med
. 2025 Jan;
222(3).
PMID: 39853307
Lysosomal stress due to the accumulation of nucleic acids (NAs) activates endosomal TLRs in macrophages. Here, we show that lysosomal RNA stress, caused by the lack of RNase T2, induces...
4.
Kitajima M, Murakami M, Ando H, Kadoya S, Iwamoto R, Kuroita T, et al.
Sci Total Environ
. 2025 Jan;
960():178209.
PMID: 39765173
International mass gathering events, such as the Olympic and Paralympic Games, face the risk of cross-border transmission of infectious diseases. We previously reported that wastewater-based epidemiology (WBE), which has attracted...
5.
Noguchi R, Yamaguchi K, Yano H, Gohda Y, Kiyomatsu T, Ota Y, et al.
Pathol Res Pract
. 2025 Jan;
266:155776.
PMID: 39742833
Pseudomyxoma peritonei (PMP) is a rare disease caused by mucin-producing tumors that develop most frequently from the appendix. The disease is characterized by the accumulation of mucin in the abdominal...
6.
Ikushima H, Yamaguchi K, Furukawa Y, Imoto S, Koda H, Mizukami T, et al.
BJC Rep
. 2024 Nov;
1(1):12.
PMID: 39516338
Cancer cells sometimes transdifferentiate into different histological type(s) and tumors with multiple histological types can share a common ancestor cell. However, diagnosis of the origin of multiple tumor lesions with...
7.
Matsuura M, Takane K, Yamaguchi K, Ikenoue T, Hatakeyama S, Kurokawa S, et al.
BJC Rep
. 2024 Nov;
1(1):18.
PMID: 39516270
Background: Endometrial cancer (EC) is one of the leading causes of cancer death among women and early detection is crucial for its successful treatment. We previously showed that cytological examination...
8.
Wu W, Zhu J, Nihira N, Togashi Y, Goda A, Koike J, et al.
Breast Cancer Res
. 2024 Oct;
26(1):146.
PMID: 39434131
Background: Epigenetic dysregulation affecting oncogenic transcription and DNA damage response is a hallmark of cancer. The histone demethylase KDM4B, a factor regulating these processes, plays important roles in estrogen receptor-mediated...
9.
Tabe S, Takeuchi K, Aoshima K, Okumura A, Yamamoto Y, Yanagisawa K, et al.
Biomaterials
. 2024 Sep;
314:122838.
PMID: 39348736
Pancreatic ductal adenocarcinoma (PDAC) is a progressive cancer with a poor prognosis. It contains a complex tumor microenvironment (TME) that includes various stromal cell types. Comprehending cellular communications within the...
10.
Meguro S, Johmura Y, Wang T, Kawakami S, Tanimoto S, Omori S, et al.
Nat Aging
. 2024 Sep;
4(11):1582-1597.
PMID: 39251867
Aging is a major risk factor for cancer, but the precise mechanism by which aging promotes carcinogenesis remains largely unknown. Here, using genetically modified mouse models, we show that p16...