Kirsty Goncalves
Overview
Explore the profile of Kirsty Goncalves including associated specialties, affiliations and a list of published articles.
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Articles
12
Citations
40
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Recent Articles
1.
Freer M, Cooper J, Goncalves K, Przyborski S
Cells
. 2024 Nov;
13(22).
PMID: 39594608
Drug discovery is associated with high levels of compound elimination in all stages of development. The current practices for the pharmacokinetic testing of intestinal absorption combine Transwell inserts with the...
2.
Costello L, Goncalves K, De Los Santos Gomez P, Hulette B, DiColandrea T, Flagler M, et al.
J Cell Physiol
. 2024 Oct;
240(1):e31463.
PMID: 39377615
Increased prevalence of skin ageing is a growing concern due to an ageing global population and has both sociological and psychological implications. The use of more clinically predictive in vitro...
3.
Goncalves K, Przyborski S
Neural Regen Res
. 2024 Aug;
20(9):2645-2654.
PMID: 39105379
JOURNAL/nrgr/04.03/01300535-202509000-00026/figure1/v/2024-11-05T132919Z/r/image-tiff Neuronal cell death and the loss of connectivity are two of the primary pathological mechanisms underlying Alzheimer's disease. The accumulation of amyloid-β peptides, a key hallmark of Alzheimer's disease,...
4.
De Los Santos Gomez P, Costello L, Goncalves K, Przyborski S
Front Med (Lausanne)
. 2024 May;
11:1355799.
PMID: 38698778
Introduction: Daily solar ultraviolet (UV) radiation has an important impact on skin health. Understanding the initial events of the UV-induced response is critical to prevent deleterious conditions. However, studies in...
5.
Costello L, Goncalves K, Maltman V, Barrett N, Shah K, Stephens A, et al.
Front Med (Lausanne)
. 2023 Nov;
10:1236790.
PMID: 38020123
Introduction: The removal of unwanted hair is a widespread grooming practice adopted by both males and females. Although many depilatory techniques are now available, shaving remains the most common, despite...
6.
Allcock B, Wei W, Goncalves K, Hoyle H, Robert A, Quelch-Cliffe R, et al.
Cells
. 2023 Oct;
12(19).
PMID: 37830622
It is widely recognised that cells respond to their microenvironment, which has implications for cell culture practices. Growth cues provided by 2D cell culture substrates are far removed from native...
7.
Freer M, Darling N, Goncalves K, Mills K, Przyborski S
Bioeng Transl Med
. 2023 May;
8(3):e10484.
PMID: 37206205
Human skin equivalents (HSEs) are an increasingly popular research tool due to limitations associated with animal testing for dermatological research. They recapitulate many aspects of skin structure and function, however,...
8.
Goncalves K, De Los Santos Gomez P, Costello L, Smith L, Mead H, Simpson A, et al.
Bioeng Transl Med
. 2023 Mar;
8(2):e10415.
PMID: 36925688
Human skin equivalents (HSEs) are a popular technology due to limitations in animal testing, particularly as they recapitulate aspects of structure and function of human skin. Many HSEs contain two...
9.
Maatta A, Nixon R, Robinson N, Ambler C, Goncalves K, Maltman V, et al.
J Cosmet Dermatol
. 2023 Jan;
22(5):1658-1669.
PMID: 36718827
Background: Retinoid signaling is an important regulator of the epidermis and skin appendages. Therefore, synthetic retinoids have been developed for therapeutic use for skin disorders such as psoriasis and acne....
10.
Costello L, Goncalves K, De Los Santos Gomez P, Simpson A, Maltman V, Ritchie P, et al.
Exp Dermatol
. 2023 Jan;
32(5):620-631.
PMID: 36695185
Skin ageing is an intricate physiological process affected by intrinsic and extrinsic factors. There is a demand to understand how the skin changes with age and photoexposure in individuals with...