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Kirk A Rockett

Explore the profile of Kirk A Rockett including associated specialties, affiliations and a list of published articles. Areas
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Articles 76
Citations 3782
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Recent Articles
1.
Opi D, Ndila C, Uyoga S, Macharia A, Fennell C, Ochola L, et al.
PLoS Genet . 2023 Sep; 19(9):e1010910. PMID: 37708213
Blood group O is associated with protection against severe malaria and reduced size and stability of P. falciparum-host red blood cell (RBC) rosettes compared to non-O blood groups. Whether the...
2.
Gilchrist J, Auckland K, Parks T, Mentzer A, Goldblatt L, Naranbhai V, et al.
PLoS Pathog . 2022 Sep; 18(9):e1010312. PMID: 36121873
Leprosy is a chronic infection of the skin and peripheral nerves caused by Mycobacterium leprae. Despite recent improvements in disease control, leprosy remains an important cause of infectious disability globally....
3.
Gilchrist J, Kariuki S, Watson J, Band G, Uyoga S, Ndila C, et al.
Elife . 2022 Jul; 11. PMID: 35866869
Invasive bacterial disease is a major cause of morbidity and mortality in African children. Despite being caused by diverse pathogens, children with sepsis are clinically indistinguishable from one another. In...
4.
Band G, Leffler E, Jallow M, Sisay-Joof F, Ndila C, Macharia A, et al.
Nature . 2021 Dec; 602(7895):106-111. PMID: 34883497
Host genetic factors can confer resistance against malaria, raising the question of whether this has led to evolutionary adaptation of parasite populations. Here we searched for association between candidate host...
5.
Ndila C, Nyirongo V, Macharia A, Jeffreys A, Rowlands K, Hubbart C, et al.
Wellcome Open Res . 2021 Oct; 5():287. PMID: 34632085
The -α -thalassaemia deletion is very common throughout Africa because it protects against malaria. When undertaking studies to investigate human genetic adaptations to malaria or other diseases, it is important...
6.
Ahouidi A, Ali M, Almagro-Garcia J, Amambua-Ngwa A, Amaratunga C, Amato R, et al.
Wellcome Open Res . 2021 Jul; 6:42. PMID: 33824913
MalariaGEN is a data-sharing network that enables groups around the world to work together on the genomic epidemiology of malaria. Here we describe a new release of curated genome variation...
7.
Amenga-Etego L, Asoala V, Agongo G, Jacob C, Goncalves S, Awandare G, et al.
Malar J . 2021 Mar; 20(1):152. PMID: 33731134
Background: Anti-malarial drug resistance remains a key concern for the global fight against malaria. In Ghana sulfadoxine-pyrimethamine (SP) is used for intermittent preventive treatment of malaria in pregnancy and combined...
8.
Muriuki J, Mentzer A, Mitchell R, Webb E, Etyang A, Kyobutungi C, et al.
Nat Med . 2021 Feb; 27(4):653-658. PMID: 33619371
Malaria and iron deficiency (ID) are common and interrelated public health problems in African children. Observational data suggest that interrupting malaria transmission reduces the prevalence of ID. To test the...
9.
Caputo B, Pichler V, Botta G, De Marco C, Hubbart C, Perugini E, et al.
Mol Ecol Resour . 2021 Feb; 21(5):1504-1516. PMID: 33590707
The two most efficient and most recently radiated Afrotropical vectors of human malaria - Anopheles coluzzii and An. gambiae - are identified by single-locus diagnostic PCR assays based on species-specific...
10.
Amuzu D, Rockett K, Leffler E, Ansah F, Amoako N, Moranga C, et al.
Exp Biol Med (Maywood) . 2020 Dec; 246(8):916-928. PMID: 33325748
Glycophorins are the most abundant sialoglycoproteins on the surface of human erythrocyte membranes. Genetic variation in glycophorin region of human chromosome 4 (containing , , and genes) is of interest...