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Kirill Pavlov

Explore the profile of Kirill Pavlov including associated specialties, affiliations and a list of published articles. Areas
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Articles 10
Citations 242
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Recent Articles
1.
Spector D, Pavlov K, Beloglazkina E, Krasnovskaya O
Int J Mol Sci . 2022 Dec; 23(23). PMID: 36498837
Pt(IV) prodrugs remain one of the most promising alternatives to conventional Pt(II) therapy due to their versatility in axial ligand choice and delayed mode of action. Selective activation from an...
2.
Spector D, Krasnovskaya O, Pavlov K, Erofeev A, Gorelkin P, Beloglazkina E, et al.
Int J Mol Sci . 2021 Apr; 22(8). PMID: 33917027
A chemo-anti-inflammatory strategy is of interest for the treatment of aggressive cancers. The platinum (IV) prodrug with non-steroidal anti-inflammatory drugs (NSAIDs) as axial ligands is designed to efficiently enter tumor...
3.
Krasnovskaya O, Spector D, Zlobin A, Pavlov K, Gorelkin P, Erofeev A, et al.
Int J Mol Sci . 2020 Dec; 21(23). PMID: 33276505
One of the hallmarks of Alzheimer's disease (AD) is the deposition of amyloid plaques in the brain parenchyma, which occurs 7-15 years before the onset of cognitive symptoms of the...
4.
Kapitau A, Goloenko I, Obyedkov V, Pavlov K, Szajda S, Waszkiewicz N
Adv Med Sci . 2019 Feb; 64(1):169-173. PMID: 30708239
Purpose: Allelic duality and functional impact of degenerate repeat at 5'- flanking promoter region in SLC6A4 gene of the serotonin transporter (5-HTTLPR), have been in the focus of investigations over...
5.
Pavlov K, Kluiver J, Meijer C, Boersma-van Ek W, Kruyt F, Karrenbeld A, et al.
J Gastrointest Oncol . 2019 Jan; 9(6):1150-1156. PMID: 30603135
Background: Diagnostic screening of premalignant esophageal lesions is hampered by the absence of biomarkers indicative of metaplastic and/or malignant transformation. The aim of this exploratory study was to investigate the...
6.
Pavlov K, Koehestanie P, Beutler J, Romkens T, Hoogeveen E, Nissen L
Frontline Gastroenterol . 2018 Sep; 9(4):323-324. PMID: 30245797
This case report describes a young, immunocompromised patient who presented with thoracic pain. After an extensive workup, she was diagnosed with a varicella zoster virus infection with involvement of the...
7.
Joseph J, Conroy S, Pavlov K, Sontakke P, Tomar T, Eggens-Meijer E, et al.
Cancer Lett . 2015 Jan; 359(1):107-16. PMID: 25592037
Glioblastoma (GBM) is the most common brain tumor in adults and the mesenchymal GBM subtype was reported to be the most malignant, presenting severe hypoxia and necrosis. Here, we investigated...
8.
Pavlov K, Honing J, Meijer C, Boersma-van Ek W, Peters F, van den Berg A, et al.
Dig Liver Dis . 2014 Dec; 47(1):73-80. PMID: 25445407
Background: Barrett's oesophagus can progress towards oesophageal adenocarcinoma through a metaplasia-dysplasia-carcinoma sequence, but the underlying mechanisms are poorly understood. The transcription factor GATA6 is known to be involved in columnar...
9.
Kosoff R, Gardiner K, Merlo L, Pavlov K, Rustgi A, Maley C
J Cell Physiol . 2011 Sep; 227(6):2654-9. PMID: 21882191
Understanding the molecular and cellular processes underlying the development, maintenance, and progression of Barrett's esophagus (BE) presents an empirical challenge because there are no simple animal models and standard 2D...
10.
Pavlov K, Maley C
Biochem Soc Trans . 2010 Mar; 38(2):331-6. PMID: 20298178
Research in Barrett's oesophagus, and neoplastic progression to OAC (oesophageal adenocarcinoma), is hobbled by the lack of good pre-clinical models that capture the evolutionary dynamics of Barrett's cell populations. Current...