Kimal Rajapakshe
Overview
Explore the profile of Kimal Rajapakshe including associated specialties, affiliations and a list of published articles.
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Articles
98
Citations
2542
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Recent Articles
1.
Jin F, Thaiparambil J, Donepudi S, Vantaku V, Piyarathna D, Maity S, et al.
Cancer Prev Res (Phila)
. 2024 Jun;
17(6):281.
PMID: 38831722
No abstract available.
2.
Napoli M, Deshpande A, Chakravarti D, Rajapakshe K, Gunaratne P, Coarfa C, et al.
Cancer Res Commun
. 2024 Jan;
4(2):264-278.
PMID: 38165157
Significance: The p63 isoforms, TAp63 and ΔNp63, control epithelial morphogenesis and tumorigenesis through the interaction with distinct transcription factors and the subsequent regulation of unique transcriptional programs.
3.
Dasgupta A, Kurenbekova L, Patel T, Rajapakshe K, Ghosal G, Nirala B, et al.
Curr Protoc
. 2023 Feb;
3(2):e670.
PMID: 36799651
Ewing Sarcoma (EwS) is the second most common malignant bone tumor in adolescents and young adults. The single-most powerful predictor of outcome in EwS is presence of metastatic burden at...
4.
Tsang S, Rainusso N, Liu M, Nomura M, Patel T, Nakahata K, et al.
Oncogene
. 2022 Nov;
41(50):5373-5384.
PMID: 36348010
Osteosarcoma, the most common pediatric bone tumor, is an aggressive heterogeneous malignancy defined by complex chromosomal aberrations. Overall survival rates remain at ~70%, but patients with chemoresistant or metastatic disease...
5.
Szwarc M, Hai L, Maurya V, Rajapakshe K, Perera D, Ittmann M, et al.
Cytokine
. 2022 Sep;
160:156022.
PMID: 36099756
Although conventional knockout and transgenic mouse models have significantly advanced our understanding of Receptor Activator of NF-κB Ligand (RANKL) signaling in intra-thymic crosstalk that establishes self-tolerance and later stages of...
6.
Srivastava A, Tommasi C, Sessions D, Mah A, Bencomo T, Garcia J, et al.
Cancer Res
. 2022 Jun;
82(17):3143-3157.
PMID: 35705526
Significance: Downregulation of RET mediated by MAB21L4-CacyBP interaction is required to induce epidermal differentiation and suppress carcinogenesis, suggesting RET inhibition as a potential therapeutic approach in squamous cell carcinoma.
7.
Stork B, Dean A, Ortiz A, Saha P, Putluri N, Planas-Silva M, et al.
Mol Metab
. 2022 May;
62:101513.
PMID: 35562082
Objective: The liver is the primary internal metabolic organ that coordinates whole body energy homeostasis in response to feeding and fasting. Genetic ablation or pharmacological inhibition of calcium/calmodulin-dependent protein kinase...
8.
Wang X, Shi Z, Lu H, Kim J, Bu W, Villalobos J, et al.
J Proteomics
. 2022 Apr;
262:104596.
PMID: 35489683
Epigenetic variation plays a significant role in normal development and human diseases including cancer, in part through post-translational modifications (PTMs) of histones. Identification and profiling of changes in histone PTMs,...
9.
Napoli M, Wu S, Gore B, Abbas H, Lee K, Checker R, et al.
Nat Commun
. 2022 Mar;
13(1):1717.
PMID: 35338160
No abstract available.
10.
De Sousa L, Rajapakshe K, Rodriguez Canales J, Chin R, Feng L, Wang Q, et al.
J Immunother Cancer
. 2022 Feb;
10(2).
PMID: 35193933
Background: The combination of ISA101, a human papilloma virus (HPV) 16 peptide vaccine, and nivolumab showed a promising response rate of 33% in patients with incurable HPV-16 cancer. Here we...