Kim M Hansen
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Explore the profile of Kim M Hansen including associated specialties, affiliations and a list of published articles.
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Recent Articles
1.
Banks W, Hansen K, Erickson M, Crews F
Brain Behav Immun
. 2023 May;
111:386-394.
PMID: 37146655
High-mobility group box 1 (HMGB1) is a ubiquitous protein that regulates transcription in the nucleus, and is an endogenous damage-associated molecular pattern molecule that activates the innate immune system. HMGB1...
2.
Erickson M, Logsdon A, Rhea E, Hansen K, Holden S, Banks W, et al.
Brain Behav Immun
. 2023 Jan;
109:251-268.
PMID: 36682515
COVID-19 and especially Long COVID are associated with severe CNS symptoms and may place persons at risk to develop long-term cognitive impairments. Here, we show that two non-infective models of...
3.
Banks W, Sharma P, Hansen K, Ludwig N, Whiteside T
Int J Mol Sci
. 2022 Oct;
23(20).
PMID: 36293369
Exosomes mediate intercellular communication, shuttling messages between cells and tissues. We explored whether exosome tissue sequestration is determined by the exosomes or the tissues using ten radiolabeled exosomes from human...
4.
Banks W, Calias P, Hansen K, Bullock K, Engelke K
J Pharm Pharmacol
. 2022 May;
74(8):1152-1159.
PMID: 35596793
Objectives: Cyclodextrins are increasingly used therapeutically. For example, 2-hydroxypropyl-ß-cyclodextrin (kleptose) is used for the treatment of Niemann-Pick disease. Kleptose crosses the blood-brain barrier poorly, in part because of a central...
5.
Banerjee S, Ghoshal S, Girardet C, DeMars K, Yang C, Niehoff M, et al.
NPJ Aging Mech Dis
. 2021 Aug;
7(1):23.
PMID: 34462439
The neural functions of adropin, a secreted peptide highly expressed in the brain, have not been investigated. In humans, adropin is highly expressed in astrocytes and peaks during critical postnatal...
6.
Ludwig N, Rao A, Sandlesh P, Yerneni S, Swain A, Bullock K, et al.
Neuro Oncol
. 2021 Jul;
24(2):197-209.
PMID: 34254643
Background: Gliomas are the most common primary brain tumors and are universally fatal. Mutations in the isocitrate dehydrogenase genes (IDH1 and IDH2) define a distinct glioma subtype associated with an...
7.
Rhea E, Logsdon A, Hansen K, Williams L, Reed M, Baumann K, et al.
Nat Neurosci
. 2020 Dec;
24(3):368-378.
PMID: 33328624
It is unclear whether severe acute respiratory syndrome coronavirus 2, which causes coronavirus disease 2019, can enter the brain. Severe acute respiratory syndrome coronavirus 2 binds to cells via the...
8.
Banks W, Sharma P, Bullock K, Hansen K, Ludwig N, Whiteside T
Int J Mol Sci
. 2020 Jun;
21(12).
PMID: 32575812
Extracellular vesicles can cross the blood-brain barrier (BBB), but little is known about passage. Here, we used multiple-time regression analysis to examine the ability of 10 exosome populations derived from...
9.
Banks W, Engelke K, Hansen K, Bullock K, Calias P
J Pharmacol Exp Ther
. 2019 Jul;
371(1):121-129.
PMID: 31320494
Cyclodextrins (CDs) have a variety of uses from acting as excipients to aiding the ability of lipid soluble drugs to cross the blood-brain barrier (BBB). They are being investigated as...
10.
Shi Z, Hansen K, Bullock K, Morofuji Y, Banks W, Brooks V
J Physiol
. 2019 Jun;
597(15):4087-4100.
PMID: 31209877
Key Points: Pregnancy increases sympathetic nerve activity (SNA), although the mechanisms responsible for this remain unknown. We tested whether insulin or leptin, two sympathoexcitatory hormones increased during pregnancy, contribute to...