Kim L Isaacs
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Explore the profile of Kim L Isaacs including associated specialties, affiliations and a list of published articles.
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Articles
55
Citations
1595
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Recent Articles
1.
Isaacs K, Sayed C
Am J Gastroenterol
. 2024 Oct;
120(1):115-124.
PMID: 39466220
Inflammatory bowel disease (IBD) is associated with extraintestinal manifestations that can affect multiple body systems. Extraintestinal manifestations (EIMSs) are seen in up to 50% of patients with IBD. Skin involvement...
2.
Chen B, Collen L, Mowat C, Isaacs K, Singh S, Kane S, et al.
Am J Med
. 2022 Sep;
135(12):1453-1460.
PMID: 36058305
Background: Emerging data showed patients with chronic inflammatory disorders, including inflammatory bowel disease, are more likely to develop atherosclerotic cardiovascular diseases, heart failure, and atrial fibrillation. This article aims to...
3.
Kanke M, Kennedy Ng M, Connelly S, Singh M, Schaner M, Shanahan M, et al.
Cell Mol Gastroenterol Hepatol
. 2022 Feb;
13(6):1717-1740.
PMID: 35158099
Background & Aims: The intestinal barrier comprises a monolayer of specialized intestinal epithelial cells (IECs) that are critical in maintaining mucosal homeostasis. Dysfunction within various IEC fractions can alter intestinal...
4.
Toyonaga T, Araba K, Kennedy M, Keith B, Wolber E, Beasley C, et al.
Sci Rep
. 2021 Jun;
11(1):13533.
PMID: 34188154
The host receptor for SARS-CoV-2, angiotensin-converting enzyme 2 (ACE2), is highly expressed in small intestine. Our aim was to study colonic ACE2 expression in Crohn's disease (CD) and non-inflammatory bowel...
5.
Somineni H, Nagpal S, Venkateswaran S, Cutler D, Okou D, Haritunians T, et al.
Am J Hum Genet
. 2021 Feb;
108(3):431-445.
PMID: 33600772
Whether or not populations diverge with respect to the genetic contribution to risk of specific complex diseases is relevant to understanding the evolution of susceptibility and origins of health disparities....
6.
Toyonaga T, Araba K, Kennedy M, Keith B, Wolber E, Beasley C, et al.
bioRxiv
. 2020 Dec;
PMID: 33269348
Background And Aims: The host receptor for SARS-CoV-2, angiotensin-converting enzyme 2 (ACE2), is highly expressed in small intestine. Our aim was to study colonic ACE2 expression in Crohn's disease (CD)...
7.
Toyonaga T, Steinbach E, Keith B, Barrow J, Schaner M, Wolber E, et al.
Cell Mol Gastroenterol Hepatol
. 2020 Jun;
10(4):779-796.
PMID: 32561494
Background & Aims: Intestinal epithelial cell (IEC) barrier dysfunction is critical to the development of Crohn's disease (CD). However, the mechanism is understudied. We recently reported increased microRNA-31-5p (miR-31-5p) expression...
8.
Feuerstein J, Isaacs K, Schneider Y, Siddique S, Falck-Ytter Y, Singh S
Gastroenterology
. 2020 Mar;
158(5):1464.
PMID: 32169295
No abstract available.
9.
Feuerstein J, Isaacs K, Schneider Y, Siddique S, Falck-Ytter Y, Singh S
Gastroenterology
. 2020 Jan;
158(5):1450-1461.
PMID: 31945371
No abstract available.
10.
Weaver K, Kochar B, Hansen J, Isaacs K, Jain A, Sheikh S, et al.
Crohns Colitis 360
. 2019 Nov;
1(3):otz029.
PMID: 31667470
Background: Risk factors for the development of chronic antibiotic dependent pouchitis (CADP) are not well understood. Methods: Using multivariable logistic regression, we compared clinical factors between 194 patients with acute...