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Jonathan J Hansen

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Articles 30
Citations 1768
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Recent Articles
1.
Arsene D, Tchaptchet S, Hansen J
Gut Microbes . 2025 Mar; 17(1):2473518. PMID: 40022675
Crohn's disease and ulcerative colitis in humans and experimental immune-mediated colitis in mice are likely due in part to overactive immune responses to resident intestinal bacteria, including certain strains of...
2.
Shore B, Fix O, Hansen J
ACG Case Rep J . 2025 Feb; 12(2):e01611. PMID: 39935769
Approximately 4 million cases of varicella-zoster occur annually, most of which are self-limited and managed conservatively with supportive care with or without oral valacyclovir. However, varicella-zoster rarely disseminates leading to...
3.
Herfarth H, Long M, Hansen J, Anderson C, English E, Buse J, et al.
Am J Gastroenterol . 2024 Apr; 119(9):1935-1938. PMID: 38668926
Introduction: After colectomy with ileoanal pouch anastomosis (IPAA), many patients develop high bowel frequency (BF) refractory to antimotility agents, despite normal IPAA morphology. Low circulating levels of glucagon-like protein-1 (GLP-1),...
4.
Sandler R, Hansen J, Peery A, Woosley J, Galanko J, Keku T
Clin Transl Gastroenterol . 2022 Feb; 13(3):e00467. PMID: 35166714
Introduction: Microscopic colitis, a common cause of diarrhea, is characterized by a largely normal appearance of the mucosa but increased numbers of lymphocytes in the epithelium and lamina propria on...
5.
Fan T, Goeser L, Lu K, Faith J, Hansen J
Cell Mol Gastroenterol Hepatol . 2021 Jul; 12(4):1373-1389. PMID: 34246809
Background & Aims: The inflammatory bowel diseases (IBDs), Crohn's disease and ulcerative colitis, are caused in part by aberrant immune responses to resident intestinal bacteria. Certain dietary components, including carbohydrates,...
6.
Toyonaga T, Araba K, Kennedy M, Keith B, Wolber E, Beasley C, et al.
Sci Rep . 2021 Jun; 11(1):13533. PMID: 34188154
The host receptor for SARS-CoV-2, angiotensin-converting enzyme 2 (ACE2), is highly expressed in small intestine. Our aim was to study colonic ACE2 expression in Crohn's disease (CD) and non-inflammatory bowel...
7.
Toyonaga T, Araba K, Kennedy M, Keith B, Wolber E, Beasley C, et al.
bioRxiv . 2020 Dec; PMID: 33269348
Background And Aims: The host receptor for SARS-CoV-2, angiotensin-converting enzyme 2 (ACE2), is highly expressed in small intestine. Our aim was to study colonic ACE2 expression in Crohn's disease (CD)...
8.
Toyonaga T, Steinbach E, Keith B, Barrow J, Schaner M, Wolber E, et al.
Cell Mol Gastroenterol Hepatol . 2020 Jun; 10(4):779-796. PMID: 32561494
Background & Aims: Intestinal epithelial cell (IEC) barrier dysfunction is critical to the development of Crohn's disease (CD). However, the mechanism is understudied. We recently reported increased microRNA-31-5p (miR-31-5p) expression...
9.
Weaver K, Kochar B, Hansen J, Isaacs K, Jain A, Sheikh S, et al.
Crohns Colitis 360 . 2019 Nov; 1(3):otz029. PMID: 31667470
Background: Risk factors for the development of chronic antibiotic dependent pouchitis (CADP) are not well understood. Methods: Using multivariable logistic regression, we compared clinical factors between 194 patients with acute...
10.
Lengfelder I, Sava I, Hansen J, Kleigrewe K, Herzog J, Neuhaus K, et al.
Front Immunol . 2019 Jul; 10:1420. PMID: 31281321
Inflammatory bowel diseases (IBD) are associated with compositional and functional changes of the intestinal microbiota, but specific contributions of individual bacteria to chronic intestinal inflammation remain unclear. is a resident...