Kim Boekelheide
Overview
Explore the profile of Kim Boekelheide including associated specialties, affiliations and a list of published articles.
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119
Citations
2478
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Recent Articles
1.
Ip B, Madnick S, Zheng S, van Tongeren T, Hall S, Li H, et al.
Toxicol Sci
. 2024 Feb;
199(2):227-245.
PMID: 38335931
Chemicals in the systemic circulation can undergo hepatic xenobiotic metabolism, generate metabolites, and exhibit altered toxicity compared with their parent compounds. This article describes a 2-chamber liver-organ coculture model in...
2.
Li H, Seada H, Madnick S, Zhao H, Chen Z, Li F, et al.
Sci Rep
. 2024 Feb;
14(1):2999.
PMID: 38316851
Endocrine-disrupting chemicals (EDCs) pose a significant threat to human well-being and the ecosystem. However, in managing the many thousands of uncharacterized chemical entities, the high-throughput screening of EDCs using relevant...
3.
Browne P, Paul Friedman K, Boekelheide K, Thomas R
Regul Toxicol Pharmacol
. 2024 Feb;
148:105579.
PMID: 38309424
Chemical safety assessment begins with defining the lowest level of chemical that alters one or more measured endpoints. This critical effect level, along with factors to account for uncertainty, is...
4.
Li H, Seada H, Madnick S, Zhao H, Chen Z, Li F, et al.
Res Sq
. 2023 Oct;
PMID: 37886543
Endocrine-disrupting chemicals (EDCs) pose a significant threat to human well-being and the ecosystem. However, in managing the many thousands of uncharacterized chemical entities, the high-throughput screening of EDCs using relevant...
5.
Li H, Madnick S, Zhao H, Hall S, Amin A, Dent M, et al.
Toxicol In Vitro
. 2023 May;
91:105624.
PMID: 37230229
The risk assessment of endocrine-disrupting chemicals (EDCs) greatly relies on in vitro screening. A 3-dimensional (3D) in vitro prostate model that can reflect physiologically-relevant prostate epithelial and stromal crosstalk can...
6.
Bianchi E, Stermer A, Nolan T, Li H, Hall S, Boekelheide K, et al.
Reprod Toxicol
. 2021 Jun;
104:44-51.
PMID: 34174366
Assessing male reproductive toxicity of environmental and therapeutic agents relies on the histopathology of the testis and epididymis in a pre-clinical setting. Animal histopathology poorly correlates with human sperm parameters,...
7.
Kelsey K, Rytel M, Dere E, Butler R, Eliot M, Huse S, et al.
Environ Health
. 2019 Oct;
18(1):91.
PMID: 31665024
Background: Exposure to the herbicide Agent Orange during the Vietnam War was widespread and is associated with numerous adverse health outcomes. A continuing concern of veterans is the possibility that...
8.
Stermer A, Wilson S, Klein D, Hall S, Boekelheide K
Biol Reprod
. 2019 Aug;
101(5):875-877.
PMID: 31426087
Histone three lysine four dimethylation (H3k4me2) in sperm is conserved across species and is linked to transgenerational epigenetic inheritance. To test whether H3K4me2 is a target for transgenerational inheritance of...
9.
Spade D, Bai C, Lambright C, Conley J, Boekelheide K, Gray L
Toxicol Lett
. 2019 Jun;
313:208.
PMID: 31253470
No abstract available.
10.
Dent M, Madnick S, Hall S, Vantangoli Policelli M, Bars C, Li H, et al.
Toxicol In Vitro
. 2019 Jun;
60:203-211.
PMID: 31154061
The development and normal function of prostate tissue depends on signalling interactions between stromal and epithelial compartments. Development of a prostate microtissue composed of these two components can help identify...