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Kiichiro Okano

Explore the profile of Kiichiro Okano including associated specialties, affiliations and a list of published articles. Areas
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Articles 21
Citations 787
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Recent Articles
1.
Sakai T, Okano K, Kohno H, Tsuneoka H
Acta Ophthalmol . 2016 May; 94(8):e765-e771. PMID: 27237048
Purpose: To compare 3-year visual outcomes after intravitreal ranibizumab (IVR) monotherapy and combination therapy of photodynamic therapy (PDT) with IVR for polypoidal choroidal vasculopathy (PCV). Methods: Medical records for 45...
2.
Kohno H, Koso H, Okano K, Sundermeier T, Saito S, Watanabe S, et al.
J Neuroinflammation . 2015 Oct; 12:188. PMID: 26458944
Background: Though accumulating evidence suggests that microglia, resident macrophages in the retina, and bone marrow-derived macrophages can cause retinal inflammation which accelerates photoreceptor cell death, the details of how these...
3.
Kuroyanagi K, Sakai T, Kohno H, Okano K, Akiyama G, Aoyagi R, et al.
Jpn J Ophthalmol . 2015 Aug; 59(6):401-8. PMID: 26318435
Purpose: Our aim was to investigate whether major histocompatibility complex (MHC) polymorphisms are associated with response to infliximab therapy in Japanese patients with Behçet uveitis (BU). Methods: We retrospectively reviewed...
4.
Arai H, Sakai T, Okano K, Aoyagi R, Imai A, Takase H, et al.
Clin Ophthalmol . 2014 May; 8:789-92. PMID: 24790408
Central retinal artery occlusion (CRAO) and multifocal retinitis with perivascular sheathing are rare in ocular toxoplasmosis. We report a case of toxoplasmic CRAO and multifocal retinitis with perivascular sheathing. A...
5.
Watanabe A, Okano K, Tsuneoka H
J Cataract Refract Surg . 2013 Oct; 39(12):1929-30. PMID: 24169230
No abstract available.
6.
Sakai T, Watanabe H, Kuroyanagi K, Akiyama G, Okano K, Kohno H, et al.
Br J Ophthalmol . 2013 Jan; 97(3):338-42. PMID: 23314623
Objective: To evaluate the changes in health-related and vision-related quality of life (HR-QoL and VR-QoL) in patients with Behçet uveitis (BU) receiving infliximab therapy. Methods: Twenty patients with recurrent BU...
7.
Akiyama G, Sakai T, Kuno N, Kimura E, Okano K, Kohno H, et al.
Mol Vis . 2013 Jan; 18:3079-86. PMID: 23304068
Purpose: To investigate the protective effect of intravitreal injection of pigment epithelium-derived factor-impregnated nanoparticles (PEDF-NPs) against photoreceptor degeneration in Royal College of Surgeons (RCS) rats. Methods: Three-week-old RCS rats received...
8.
Gao S, Maeda T, Okano K, Palczewski K
Invest Ophthalmol Vis Sci . 2012 Aug; 53(10):6314-23. PMID: 22918645
Purpose: To design and develop a drug-delivery system containing a combination of poly(D,L-lactide-co-glycolide) (PLGA) microparticles and alginate hydrogel for sustained release of retinoids to treat retinal blinding diseases that result...
9.
Okano K, Maeda A, Chen Y, Chauhan V, Tang J, Palczewska G, et al.
J Neurochem . 2012 Jan; 121(1):146-56. PMID: 22220722
All-trans-retinal and its condensation-products can cause retinal degeneration in a light-dependent manner and contribute to the pathogenesis of human macular diseases such as Stargardt's disease and age-related macular degeneration. Although...
10.
Maeda A, Golczak M, Chen Y, Okano K, Kohno H, Shiose S, et al.
Nat Chem Biol . 2011 Dec; 8(2):170-8. PMID: 22198730
Vertebrate vision is initiated by photoisomerization of the visual pigment chromophore 11-cis-retinal and is maintained by continuous regeneration of this retinoid through a series of reactions termed the retinoid cycle....