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Kieran C Murphy

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Articles 83
Citations 4611
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Recent Articles
1.
Walsh D, Murphy N, Evans S, Murphy K, Guerandel A, Doherty A, et al.
Ir J Psychol Med . 2024 Feb; :1-8. PMID: 38351631
Objectives: This study aimed to evaluate the proportion of Irish medical students exposed to 'badmouthing' of different specialities and to ascertain: the degree of criticism of specialities based on the...
2.
Ge R, Ching C, Bassett A, Kushan L, Antshel K, van Amelsvoort T, et al.
Hum Brain Mapp . 2024 Jan; 45(1):e26553. PMID: 38224541
22q11.2 deletion syndrome (22q11DS) is the most frequently occurring microdeletion in humans. It is associated with a significant impact on brain structure, including prominent reductions in gray matter volume (GMV),...
3.
Zhao Y, Wang Y, Shi L, McDonald-McGinn D, Crowley T, McGinn D, et al.
NPJ Genom Med . 2023 Jul; 8(1):17. PMID: 37463940
Congenital heart disease (CHD) affecting the conotruncal region of the heart, occurs in 40-50% of patients with 22q11.2 deletion syndrome (22q11.2DS). This syndrome is a rare disorder with relative genetic...
4.
Trubetskoy V, Pardinas A, Qi T, Panagiotaropoulou G, Awasthi S, Bigdeli T, et al.
Nature . 2022 Apr; 604(7906):502-508. PMID: 35396580
Schizophrenia has a heritability of 60-80%, much of which is attributable to common risk alleles. Here, in a two-stage genome-wide association study of up to 76,755 individuals with schizophrenia and...
5.
Hartnett Y, Alshurafa K, McAndrew J, Daly D, Alsaffar M, Cotter D, et al.
Ir J Psychol Med . 2022 Mar; 40(3):411-417. PMID: 35285434
Objectives: To examine the impact of the first full year of the COVID-19 pandemic and its associated restrictions on the volume and nature of psychiatric presentations to an emergency department...
6.
Hannon E, Dempster E, Mansell G, Burrage J, Bass N, Bohlken M, et al.
Elife . 2021 Mar; 10. PMID: 33646943
We performed a systematic analysis of blood DNA methylation profiles from 4483 participants from seven independent cohorts identifying differentially methylated positions (DMPs) associated with psychosis, schizophrenia, and treatment-resistant schizophrenia. Psychosis...
7.
Davies R, Fiksinski A, Breetvelt E, Williams N, Hooper S, Monfeuga T, et al.
Nat Med . 2020 Nov; 26(12):1912-1918. PMID: 33169016
The 22q11.2 deletion syndrome (22q11DS) is associated with a 20-25% risk of schizophrenia. In a cohort of 962 individuals with 22q11DS, we examined the shared genetic basis between schizophrenia and...
8.
McAndrew J, OLeary J, Cotter D, Cannon M, MacHale S, Murphy K, et al.
Ir J Psychol Med . 2020 Sep; 38(2):108-115. PMID: 32996441
Objectives: To determine if the initial COVID-19 societal restrictions, introduced in Ireland in March 2020, impacted on the number and nature of psychiatry presentations to the emergency department (ED) of...
9.
Russell V, ORourke L, Murphy K
Ir J Psychol Med . 2020 May; 37(2):73-76. PMID: 32349854
Irish medical schools attract an increasingly diverse student population and produce graduates who will practise in many parts of the world. There are particular implications in this for the planning...
10.
Ching C, Gutman B, Sun D, Villalon Reina J, Ragothaman A, Isaev D, et al.
Am J Psychiatry . 2020 Feb; 177(7):589-600. PMID: 32046535
Objective: 22q11.2 deletion syndrome (22q11DS) is among the strongest known genetic risk factors for schizophrenia. Previous studies have reported variable alterations in subcortical brain structures in 22q11DS. To better characterize...