Khushboo Sethi
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Explore the profile of Khushboo Sethi including associated specialties, affiliations and a list of published articles.
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Articles
16
Citations
23
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Recent Articles
1.
Rani R, Sethi K, Gupta S, Virmani N, Kumar S, Kumar R
Acta Trop
. 2023 Jul;
245:106980.
PMID: 37419379
Trypanosoma evansi, a hemoflagellate poses huge economic threat to the livestock industry of several countries of Asia, Africa, South America and Europe continents of the world. Limited number of available...
2.
Gupta S, Vohra S, Sethi K, Rani R, Gupta S, Kumar S, et al.
Mol Biochem Parasitol
. 2023 Apr;
254:111562.
PMID: 37084956
Current chemotherapy against the Surra organism, Trypanosoma evansi has several limitations in terms of efficacy, toxicity, availability and emerging resistance. These reasons make the search of new chemo-preventive and chemo-therapeutic...
3.
Kumar R, Sethi K, Batra K, Kumar S, Jain S, Kumar S
Vet Parasitol
. 2023 Jan;
314:109866.
PMID: 36608386
Trypanosoma evansi, a hemoflagellate protozoan, leads to wasting disease, surra in livestock animals causing huge economic losses. Currently, the preferred assay for surra diagnosis is whole cell lysate (WCL) based...
4.
Kumar R, Sethi K, Jindal N, Kumar S, Tripathi B
Res Vet Sci
. 2022 Oct;
152:604-609.
PMID: 36201907
Surra caused by an extracellular hemoflagellate, Trypanosoma evansi, leads to severe economic loss to livestock productivity in India. Among the various mammalian pathogenic trypanosomes, T. evansi has the widest host...
5.
Rani R, Sethi K, Gupta S, Varma R, Kumar R
Curr Top Med Chem
. 2022 Sep;
22(25):2087-2105.
PMID: 36098414
Naphthoquinone is a heterocyclic moiety whose natural derivatives are present as bioactive compounds in many plants and have stimulated a resurgence of interest in the past decades due to their...
6.
Kumar R, Sethi K, Gaur D, Goyal S, Kumar S, Jain S, et al.
Vet Parasitol
. 2022 Aug;
310:109776.
PMID: 35987128
Serodiagnosis of surra, caused by Trypanosoma evansi, is still based on native antigens purified from bloodstream form of T. evansi grown in rodents. In order to investigate prospective diagnostic possibilities...
7.
Gupta S, Vohra S, Sethi K, Gupta S, Kumar S, Kumar R
Parasitol Int
. 2022 Jul;
91:102632.
PMID: 35870741
The kinetoplastid protozoan parasite, Trypanosoma evansi causes a fatal disease condition known as Surra in equines throughout the globe. Disease condition being acute in nature, entrust a huge economic and...
8.
Gupta S, Vohra S, Sethi K, Gupta S, Bera B, Kumar S, et al.
Trop Anim Health Prod
. 2022 Jul;
54(4):240.
PMID: 35869164
High cytotoxicity and increasing resistance reports of existing chemotherapeutic agents against T. evansi have raised the demand for novel, potent, and high therapeutic index molecules for the treatment of surra...
9.
Rani R, Sethi K, Kumar S, Varma R, Kumar R
Chem Biol Drug Des
. 2022 Jul;
100(6):786-817.
PMID: 35852920
Over the past decades, a number of 1,4-naphthoquinones have been isolated from natural resources and several of naphthoquinone derivatives with diverse structural motif have been synthesized; they possess a multitude...
10.
Bhutia W, Gupta S, Rani R, Batra K, Sethi K, Kumar S, et al.
Vet Res Commun
. 2022 Jun;
47(2):473-485.
PMID: 35751782
Trypanosoma evansi is a causative agent of chronic wasting and fatal disease of livestock and wild animals known as surra. In this study, repurposing approach based on drug target was...