Kewei Rong
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Explore the profile of Kewei Rong including associated specialties, affiliations and a list of published articles.
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Articles
18
Citations
132
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Recent Articles
1.
Cao X, Rong K, Li Y, Zhang P, Liu K, Cui L, et al.
J Orthop Translat
. 2025 Jan;
50:158-173.
PMID: 39876975
Background: RANKL and SCLEROSTIN antibodies have provided a strong effective choice for treating osteoporosis in the past years, which suggested novel molecular target identification and therapeutic strategies development are important...
2.
Cao X, Liu K, Yuan J, Hua Q, Rong K, Zhou T, et al.
J Adv Res
. 2025 Jan;
PMID: 39826612
Introduction: Bone homeostasis between osteoclast bone resorption and osteoblastic bone formation is tightly regulated by a series of factors such as the receptor activator of nuclear factor-κB ligand (RANKL). Denosumab...
3.
Zhao C, Rong K, Liu P, Kong K, Li H, Zhang P, et al.
Commun Biol
. 2024 Aug;
7(1):962.
PMID: 39122919
With increases in life expectancy, the number of patients requiring joint replacement therapy and experiencing periprosthetic osteolysis, the most common complication leading to implant failure, is growing or underestimated. In...
4.
Li B, Hu Y, Chen Y, Liu K, Rong K, Hua Q, et al.
Biochem Pharmacol
. 2024 Jun;
226:116389.
PMID: 38914318
Intervertebral disc degeneration (IVDD) is a common degenerative disease which is closely related to low back pain (LBP) and brings huge economic and social burdens. In this study, we explored...
5.
Kong K, Jin M, Zhao C, Qiao H, Chen X, Li B, et al.
iScience
. 2023 Nov;
26(11):108119.
PMID: 37965144
Patients with OA and varus knees are subject to abnormal mechanical environment and objective of this study was to investigate the molecular mechanisms underlying chondrocyte senescence caused by mechanical overloading...
6.
Zhang P, Rong K, Guo J, Cui L, Kong K, Zhao C, et al.
Biomed Pharmacother
. 2023 Aug;
165:115252.
PMID: 37536034
Intervertebral disc degeneration (IVDD) leads to a series of degenerative spine diseases. Clinical treatment of IVDD is mainly surgery, lacking effective drugs to alleviate intervertebral disc degeneration. In this study,...
7.
Yu Y, Rong K, Yao D, Zhang Q, Cao X, Rao B, et al.
Nat Commun
. 2023 Jul;
14(1):4048.
PMID: 37422472
Hypophosphatasia (HPP) is a metabolic bone disease that manifests as developmental abnormalities in bone and dental tissues. HPP patients exhibit hypo-mineralization and osteopenia due to the deficiency or malfunction of...
8.
Wang X, Zhou T, Yang X, Cao X, Jin G, Zhang P, et al.
Adv Sci (Weinh)
. 2023 Mar;
10(14):e2204438.
PMID: 36965071
Chemoresistance is the main obstacle in osteosarcoma (OS) treatment; however, the underlying mechanism remains unclear. In this study, it is discovered that DDRGK domain-containing protein 1 (DDRGK1) plays a fundamental...
9.
Yang X, Chen Y, Guo J, Li J, Zhang P, Yang H, et al.
Adv Sci (Weinh)
. 2023 Mar;
10(13):e2207216.
PMID: 36951540
Intervertebral disc degeneration (IVDD)-induced lower back pain (LBP) is a common problem worldwide. The underlying mechanism is partially accredited to ferroptosis, based on sequencing analyses of IVDD patients from the...
10.
Kong K, Chang Y, Qiao H, Zhao C, Chen X, Rong K, et al.
J Transl Med
. 2022 Nov;
20(1):549.
PMID: 36435786
Background: The COVID-19 pandemic has become a huge threat to human health, infecting millions of people worldwide and causing enormous economic losses. Many novel small molecule drugs have been developed...