Kevin Weinfurt
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Explore the profile of Kevin Weinfurt including associated specialties, affiliations and a list of published articles.
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3188
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Recent Articles
11.
Kamat S, Yaworsky A, Guillemin I, Krohe M, Litcher-Kelly L, McLafferty M, et al.
J Allergy Clin Immunol Pract
. 2022 Apr;
10(7):1856-1863.e3.
PMID: 35398552
Background: Pediatric patients with eosinophilic esophagitis (EoE) experience heterogeneous symptoms and the patient's age may preclude reliable self-report of symptoms. Objective: The goal of this study was to develop a...
12.
Federico C, Heagerty P, Lantos J, ORourke P, Rahimzadeh V, Sugarman J, et al.
Contemp Clin Trials
. 2022 Feb;
115:106703.
PMID: 35176501
Stepped-wedge cluster randomized trial (SW-CRT) designs are increasingly employed in pragmatic research; they differ from traditional parallel cluster randomized trials in which an intervention is delivered to a subset of...
13.
Sandy L, Glorioso T, Weinfurt K, Sugarman J, Peterson P, Glasgow R, et al.
Medicine (Baltimore)
. 2021 Dec;
100(51):e28136.
PMID: 34941059
Opt-out procedures are sometimes used instead of standard consent practices to enable patients to exercise their autonomous preferences regarding research participation while reducing patient and researcher burden. However, little is...
14.
Incentives and payments in pragmatic clinical trials: Scientific, ethical, and policy considerations
Garland A, Weinfurt K, Sugarman J
Clin Trials
. 2021 Nov;
18(6):699-705.
PMID: 34766524
Pragmatic clinical trials are increasingly used to generate knowledge about real-world clinical interventions. However, they involve some distinctive ethical and regulatory challenges. In this article, we examine a set of...
15.
Morain S, Mathews D, Weinfurt K, May E, Bollinger J, Geller G, et al.
Learn Health Syst
. 2021 Oct;
5(4):e10245.
PMID: 34667872
Context: Pragmatic clinical trials (PCTs), which are becoming widespread since they are relatively inexpensive and offer important benefits for healthcare decision-making, can also present practical, ethical, and legal challenges. One...
16.
Morain S, Mathews D, Geller G, Bollinger J, Weinfurt K, Jarvik J, et al.
Healthc (Amst)
. 2021 Oct;
9(4):100586.
PMID: 34600345
While the embedded nature of pragmatic clinical trials (PCTs) can improve the efficiency and relevance of research for multiple stakeholders, embedding research into ongoing clinical care can also involve ethical...
17.
Coles T, Hernandez A, Reeve B, Cook K, Edwards M, Boutin M, et al.
Health Qual Life Outcomes
. 2021 Jun;
19(1):164.
PMID: 34120618
Objectives: There has been limited success in achieving integration of patient-reported outcomes (PROs) in clinical trials. We describe how stakeholders envision a solution to this challenge. Methods: Stakeholders from academia,...
18.
Volkner C, Liedtke M, Petters J, Lukas J, Murua Escobar H, Knuebel G, et al.
Stem Cell Res
. 2020 Dec;
50:102127.
PMID: 33360098
Niemann-Pick disease Type C (NPC) is a rare progressive neurodegenerative disorder with an incidence of 1:120,000 caused by mutations in the NPC1 or NPC2 gene leading to a massive cholesterol...
19.
Scales Jr C, Lai H, Desai A, Antonelli J, Maalouf N, Tasian G, et al.
J Endourol
. 2020 Oct;
35(6):761-768.
PMID: 33081503
Ureteral stents are commonly employed after ureteroscopy to treat urinary stone disease, but the devices impose a substantial burden of stent-associated symptoms (SAS), including pain and urinary side effects. The...
20.
Roberts M, Fisher D, Parker L, Darnell D, Sugarman J, Carrithers J, et al.
Ethics Hum Res
. 2020 Sep;
42(5):29-37.
PMID: 32937035
The implementation of pragmatic clinical trials (PCTs) can be accompanied by unique regulatory challenges. In this paper, we describe the experience and management of regulatory noncompliance during a 25-site acute...