Kevin M Dean
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Explore the profile of Kevin M Dean including associated specialties, affiliations and a list of published articles.
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48
Citations
1193
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Recent Articles
1.
Jeppesen D, Sanchez Z, Kelley N, Hayes J, Ambroise J, Koory E, et al.
Nat Cell Biol
. 2025 Feb;
27(3):438-448.
PMID: 39984653
Cells secrete a large variety of extracellular vesicles (EVs) to engage in cell-to-cell and cell-to-environment intercellular communication. EVs are functionally involved in many physiological and pathological processes by interacting with...
2.
Lin J, Marin Z, Wang X, Borges H, NGuetta P, Luo X, et al.
bioRxiv
. 2025 Feb;
PMID: 39896507
Understanding how subcellular structures and events shape tissue-wide phenomena remains a central challenge in biology. We present Multiscale Cleared Tissue Axially Swept Light-Sheet Microscopy (MCT-ASLM), a platform combining cm-scale imaging...
3.
McFadden C, Marin Z, Chen B, Daetwyler S, Wang X, Rajendran D, et al.
Biomed Opt Express
. 2024 Sep;
15(8):4498-4512.
PMID: 39346993
Adaptive optics (AO) can restore diffraction-limited performance when imaging beyond superficial cell layers and , and as such, is of interest for advanced 3D microscopy methods such as light-sheet fluorescence...
4.
Lin J, Mehra D, Marin Z, Wang X, Borges H, Shen Q, et al.
Biomed Opt Express
. 2024 Sep;
15(9):5314-5327.
PMID: 39296406
We present a mechanically sheared image acquisition format for upright and open-top light-sheet microscopes that automatically places data in its proper spatial context. This approach, which reduces computational post-processing and...
5.
Marin Z, Wang X, Collison D, McFadden C, Lin J, Borges H, et al.
Nat Methods
. 2024 Sep;
21(11):1967-1969.
PMID: 39261640
No abstract available.
6.
Ju R, Falconer A, Schmidt C, Enriquez Martinez M, Dean K, Fiolka R, et al.
Nat Cell Biol
. 2024 Aug;
26(9):1520-1534.
PMID: 39160291
Cells migrating through complex three-dimensional environments experience considerable physical challenges, including tensile stress and compression. To move, cells need to resist these forces while also squeezing the large nucleus through...
7.
Nanes B, Bhatt K, Azarova E, Rajendran D, Munawar S, Isogai T, et al.
Dev Cell
. 2024 Jul;
59(20):2759-2771.e11.
PMID: 39002537
Keratin intermediate filaments confer structural stability to epithelial tissues, but the reason this simple mechanical function requires a protein family with 54 isoforms is not understood. During skin wound healing,...
8.
Driscoll M, Welf E, Weems A, Sapoznik E, Zhou F, Murali V, et al.
Dev Cell
. 2024 Jun;
59(18):2414-2428.e8.
PMID: 38870943
In crowded microenvironments, migrating cells must find or make a path. Amoeboid cells are thought to find a path by deforming their bodies to squeeze through tight spaces. Yet, some...
9.
Lin J, Mehra D, Marin Z, Wang X, Borges H, Shen Q, et al.
bioRxiv
. 2024 Apr;
PMID: 38645073
We present a mechanically sheared image acquisition format for upright and open-top light-sheet microscopes that automatically places data in its proper spatial context. This approach, which reduces computational post-processing and...
10.
McFadden C, Marin Z, Chen B, Daetwyler S, Wang X, Rajendran D, et al.
bioRxiv
. 2024 Apr;
PMID: 38562744
Adaptive optics (AO) can restore diffraction limited performance when imaging beyond superficial cell layers and , and as such is of interest for advanced 3D microscopy methods such as light-sheet...