Kevin L Behar
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Explore the profile of Kevin L Behar including associated specialties, affiliations and a list of published articles.
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85
Citations
3367
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Recent Articles
1.
Mangia S, DiNuzzo M, Ponticorvo S, Dienel G, Behar K, Benveniste H, et al.
Sci Rep
. 2025 Mar;
15(1):8127.
PMID: 40057554
Despite extensive research on neuroimaging correlates of human brain aging, there is little mechanistic insight into how they are linked to loss of brain function. Previous studies on the role...
2.
Gunawan F, Matson B, Coppoli A, Jiang L, Ding Y, Perry R, et al.
Obesity (Silver Spring)
. 2024 May;
32(7):1329-1338.
PMID: 38764181
Objective: Obesity is associated with alterations in eating behavior and neurocognitive function. In this study, we investigate the effect of obesity on brain energy utilization, including brain glucose transport and...
3.
Ip K, Thomas M, Behar K, de Graaf R, De Feyter H
Front Cell Neurosci
. 2023 May;
17:1130816.
PMID: 37187610
Introduction: There is a lack of robust metabolic imaging techniques that can be routinely applied to characterize lesions in patients with brain tumors. Here we explore in an animal model...
4.
DiNuzzo M, Dienel G, Behar K, Petroff O, Benveniste H, Hyder F, et al.
J Neurochem
. 2023 May;
168(5):632-662.
PMID: 37150946
During transient brain activation cerebral blood flow (CBF) increases substantially more than cerebral metabolic rate of oxygen consumption (CMRO) resulting in blood hyperoxygenation, the basis of BOLD-fMRI contrast. Explanations for...
5.
Chowdhury G, Behar K, Mason G, Rothman D, de Graaf R
NMR Biomed
. 2023 Apr;
37(6):e4957.
PMID: 37088548
The olfactory bulb (OB) plays a fundamental role in the sense of smell and has been implicated in several pathologies, including Alzheimer's disease. Despite its importance, high metabolic activity and...
6.
Rothman D, Behar K, Petroff O, Shulman R
NMR Biomed
. 2022 Nov;
36(4):e4879.
PMID: 36424353
This paper provides a brief description of the early use of ex vivo nuclear magnetic resonance (NMR) studies of tissue and tissue extracts performed in the laboratory of Dr. Robert...
7.
Rothman D, Behar K, Dienel G
J Neurochem
. 2022 Sep;
168(5):555-591.
PMID: 36089566
The ~1:1 stoichiometry between the rates of neuronal glucose oxidation (CMR) and glutamate (Glu)/γ-aminobutyric acid (GABA)-glutamine (Gln) neurotransmitter (NT) cycling between neurons and astrocytes (V) has been firmly established. However,...
8.
Koush Y, Rothman D, Behar K, de Graaf R, Hyder F
J Cereb Blood Flow Metab
. 2022 Jan;
42(6):911-934.
PMID: 35078383
While functional MRI (fMRI) localizes brain activation and deactivation, functional MRS (fMRS) provides insights into the underlying metabolic conditions. There is much interest in measuring task-induced and resting levels of...
9.
McNair L, Mason G, Chowdhury G, Jiang L, Ma X, Rothman D, et al.
J Cereb Blood Flow Metab
. 2022 Jan;
42(8):1507-1523.
PMID: 35048735
Anaplerosis occurs predominately in astroglia through the action of pyruvate carboxylase (PC). The rate of PC (Vpc) has been reported for cerebral cortex (or whole brain) of awake humans and...
10.
Rothman D, Dienel G, Behar K, Hyder F, DiNuzzo M, Giove F, et al.
J Cereb Blood Flow Metab
. 2022 Jan;
42(5):844-860.
PMID: 34994222
Over the last two decades, it has been established that glucose metabolic fluxes in neurons and astrocytes are proportional to the rates of the glutamate/GABA-glutamine neurotransmitter cycles in close to...