Golam M I Chowdhury
Overview
Explore the profile of Golam M I Chowdhury including associated specialties, affiliations and a list of published articles.
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16
Citations
542
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Recent Articles
1.
Chowdhury G, Behar K, Mason G, Rothman D, de Graaf R
NMR Biomed
. 2023 Apr;
37(6):e4957.
PMID: 37088548
The olfactory bulb (OB) plays a fundamental role in the sense of smell and has been implicated in several pathologies, including Alzheimer's disease. Despite its importance, high metabolic activity and...
2.
Pothula S, Kato T, Liu R, Wu M, Gerhard D, Shinohara R, et al.
Mol Psychiatry
. 2020 Jun;
26(9):5097-5111.
PMID: 32488125
Both the NMDA receptor (NMDAR) positive allosteric modulator (PAM), and antagonist, can exert rapid antidepressant effects as shown in several animal and human studies. However, how this bidirectional modulation of...
3.
Kosten L, Chowdhury G, Mingote S, Staelens S, Rothman D, Behar K, et al.
Neurochem Int
. 2019 Jul;
129:104508.
PMID: 31326460
Glutaminase mediates the recycling of neurotransmitter glutamate, supporting most excitatory neurotransmission in the mammalian central nervous system. A constitutive heterozygous reduction in GLS1 engenders in mice a model of schizophrenia...
4.
Abdallah C, De Feyter H, Averill L, Jiang L, Averill C, Chowdhury G, et al.
Neuropsychopharmacology
. 2018 Jul;
43(10):2154-2160.
PMID: 29977074
The ability of ketamine administration to activate prefrontal glutamate neurotransmission is thought to be a key mechanism contributing to its transient psychotomimetic effects and its delayed and sustained antidepressant effects....
5.
Chowdhury G, Wang P, Ciardi A, Mamillapalli R, Johnson J, Zhu W, et al.
Diabetes
. 2017 Apr;
66(7):1979-1989.
PMID: 28416628
The objectives of this study were to understand the role of glutamatergic neurotransmission in the ventromedial hypothalamus (VMH) in response to hypoglycemia and to elucidate the effects of recurrent hypoglycemia...
6.
Chowdhury G, Jiang L, Rothman D, Behar K
J Cereb Blood Flow Metab
. 2014 May;
34(7):1233-42.
PMID: 24780902
The capacity of ketone bodies to replace glucose in support of neuronal function is unresolved. Here, we determined the contributions of glucose and ketone bodies to neocortical oxidative metabolism over...
7.
de Graaf R, Chowdhury G, Behar K
Anal Chem
. 2014 Apr;
86(10):5032-8.
PMID: 24773047
NMR spectroscopy in combination with (13)C-labeled substrate infusion is a unique technique to obtain information about dynamic metabolic fluxes noninvasively in vivo. In many cases, the in vivo information content...
8.
Patel A, Lai J, Chowdhury G, Hyder F, Rothman D, Shulman R, et al.
Proc Natl Acad Sci U S A
. 2014 Apr;
111(14):5385-90.
PMID: 24706914
Previous (13)C magnetic resonance spectroscopy experiments have shown that over a wide range of neuronal activity, approximately one molecule of glucose is oxidized for every molecule of glutamate released by...
9.
Chowdhury G, Behar K, Cho W, Thomas M, Rothman D, Sanacora G
Biol Psychiatry
. 2011 Dec;
71(11):1022-5.
PMID: 22169441
Ketamine has recently gained significant attention owing to its psychotomimetic and more recently discovered rapid antidepressant-like properties. ¹H-[¹³C]-nuclear magnetic resonance studies were employed to explore potential physiological processes underlying these...
10.
de Graaf R, Chowdhury G, Behar K
Anal Chem
. 2010 Dec;
83(1):216-24.
PMID: 21142125
Extracting quantitative information about absolute concentrations from high-resolution (1)H NMR spectra of complex mixtures such as brain extracts remains challenging. Partial overlap of resonances complicates integration, whereas simple line fitting...