Kevin J McElwee
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Explore the profile of Kevin J McElwee including associated specialties, affiliations and a list of published articles.
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64
Citations
1016
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Recent Articles
1.
McElwee K, McElwee K, Sundberg J
Expert Opin Drug Discov
. 2025 Mar;
:1-20.
PMID: 40029254
Introduction: Androgenetic alopecia (AGA) is the most common cause of hair loss worldwide. The significant psychological and social impact of AGA continues to drive demand for more effective treatments beyond...
2.
Guo H, Lai H, Long B, Xu L, Chun Wang E, Shapiro J, et al.
Exp Dermatol
. 2024 Oct;
33(10):e15182.
PMID: 39367575
Stress may play a key role in alopecia areata (AA), though the exact interactions of stress with AA remain undefined. Corticotropin-releasing hormone (CRH), the proximal regulator of the stress axis,...
3.
Guo H, Ye Z, Chen S, McElwee K
Expert Opin Drug Discov
. 2024 Oct;
19(11):1321-1338.
PMID: 39360759
Introduction: The autoimmune hair loss condition alopecia areata (AA) exacts a substantial psychological and socioeconomic toll on patients. Biotechnology companies, dermatology clinics, and research institutions are dedicated to understanding AA...
4.
Sundberg J, Wang E, McElwee K
Curr Protoc
. 2024 Aug;
4(8):e1113.
PMID: 39105684
Alopecia areata is the second most common form of hair loss in humans after androgenetic alopecia. Although a variety of animal models for alopecia areata have been described, currently the...
5.
Wang X, Ramos R, Phan A, Yamaga K, Flesher J, Jiang S, et al.
Nature
. 2023 Jun;
618(7966):808-817.
PMID: 37344645
Niche signals maintain stem cells in a prolonged quiescence or transiently activate them for proper regeneration. Altering balanced niche signalling can lead to regenerative disorders. Melanocytic skin nevi in human...
6.
Zeng Z, Li S, Ye Y, Ling Y, Gong Y, Zi X, et al.
Exp Dermatol
. 2023 Apr;
32(7):1108-1119.
PMID: 37114716
Atopy may be a facilitating factor in some alopecia areata (AA) patients with early disease onset and more severe/extensive AA. The underlying immune mechanisms are unknown, but allergen responses may...
7.
Wang E, McElwee K
Methods Mol Biol
. 2020 Apr;
2154:121-131.
PMID: 32314212
Surgical induction of alopecia areata (AA) via full-thickness grafting of spontaneous AA-affected C3H/HeJ mouse skin to naïve recipients has been a primary method of transferring the AA disease model phenotype....
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Siah T, Guo H, Chu T, Santos L, Nakamura H, Leung G, et al.
Exp Dermatol
. 2020 Jan;
29(3):334-340.
PMID: 31984508
Background: Platelet-rich plasma (PRP), processed from autologous peripheral blood, is used to treat androgenetic alopecia (AGA). Objective: To determine the efficacy of PRP for hair growth promotion in AGA patients...
10.
Broadley D, McElwee K
Exp Dermatol
. 2020 Jan;
29(3):208-222.
PMID: 31960494
A 3500-year-old papyrus from ancient Egypt provides a list of treatments for many diseases including "bite hair loss," most likely alopecia areata (AA). The treatment of AA remained largely unchanged...