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Kevin J Klos

Explore the profile of Kevin J Klos including associated specialties, affiliations and a list of published articles. Areas
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Articles 15
Citations 869
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Recent Articles
1.
Espay A, Pagan F, Walter B, Morgan J, Elmer L, Waters C, et al.
Neurol Clin Pract . 2017 Mar; 7(1):86-93. PMID: 28243505
Purpose Of Review: To help clinicians optimize the conversion of a patient's Parkinson disease pharmacotherapy from immediate-release carbidopa/levodopa (IR CD/LD) to an extended-release formulation (ER CD/LD). Recent Findings: Eleven movement...
2.
Dickson D, Fujishiro H, Orr C, DelleDonne A, Josephs K, Frigerio R, et al.
Parkinsonism Relat Disord . 2010 Jan; 15 Suppl 3:S1-5. PMID: 20082965
Non-motor manifestations of Parkinson disease (PD) are common and some may actually antedate motor dysfunction. Extrapyramidal signs in PD are tightly linked to striatonigral dopaminergic denervation associated with neuronal loss...
3.
Frigerio R, Fujishiro H, Maraganore D, Klos K, DelleDonne A, Heckman M, et al.
Arch Neurol . 2009 Sep; 66(9):1114-9. PMID: 19752300
Objective: To explore whether associations of potential risk factors for incidental Lewy body disease (iLBD) are similar to those for Parkinson disease (PD). Design: Brain autopsy study (1988-2004) of subjects...
4.
Frigerio R, Fujishiro H, Ahn T, Josephs K, Maraganore D, DelleDonne A, et al.
Neurobiol Aging . 2009 Jun; 32(5):857-63. PMID: 19560232
Lewy pathology occurs in 8-17% of neurologically normal people age >60, termed incidental Lewy body disease (iLBD). It is often assumed to represent preclinical Parkinson disease (PD). However, some iLBD...
5.
DelleDonne A, Klos K, Fujishiro H, Ahmed Z, Parisi J, Josephs K, et al.
Arch Neurol . 2008 Aug; 65(8):1074-80. PMID: 18695057
Background: The significance of Lewy bodies detected at autopsy in the brains of clinically normal individuals is uncertain but may represent preclinical Parkinson disease (PD). Objective: To determine whether diminished...
6.
Fujishiro H, Frigerio R, Burnett M, Klos K, Josephs K, DelleDonne A, et al.
Mov Disord . 2008 Apr; 23(8):1085-92. PMID: 18442129
Attention has been drawn to cardiac sympathetic denervation in Parkinson's disease (PD) based on clinical studies using [123I] metaiodobenzylguanidine scintigraphy; however, the histologic correlates and time course of cardiac sympathetic...
7.
Dickson D, Fujishiro H, DelleDonne A, Menke J, Ahmed Z, Klos K, et al.
Acta Neuropathol . 2008 Feb; 115(4):437-44. PMID: 18264713
Lewy bodies, the histologic hallmark of Parkinson's disease (PD), are detected in the brains of about 10% of clinically normal people over the age of 60 years. When Lewy bodies...
8.
McKeon A, Josephs K, Klos K, Hecksel K, Bower J, Bostwick J, et al.
Parkinsonism Relat Disord . 2007 Jun; 13(8):516-9. PMID: 17544807
Unusual compulsive behaviors (weighing, card and video game playing, fishing, gardening, intense interest in established hobbies, locking and unlocking doors, repetitive dressing and undressing) occurred in relation to dopamine agonist...
9.
Davidzon G, Greene P, Mancuso M, Klos K, Ahlskog J, Hirano M, et al.
Ann Neurol . 2006 Apr; 59(5):859-62. PMID: 16634032
Objective: To define the molecular etiology of early-onset parkinsonism and peripheral neuropathy. Methods: Two sisters had early-onset parkinsonism (dystonic toe curling, action tremor, masked face, bradykinesia, stooped posture, and rigidity),...
10.
Klos K, Wijdicks E
Neurology . 2006 Jan; 66(2):E11. PMID: 16434643
No abstract available.