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Kevin H Liu

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Articles 6
Citations 118
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Recent Articles
1.
Bond S, King E, Walker S, Yang C, Liu Y, Liu K, et al.
Nat Commun . 2025 Mar; 16(1):2338. PMID: 40057508
During mitochondrial damage, information is relayed between the mitochondria and nucleus to coordinate precise responses to preserve cellular health. One such pathway is the mitochondrial integrated stress response (mtISR), which...
2.
Fu N, Pal B, Chen Y, Jackling F, Milevskiy M, Vaillant F, et al.
Dev Cell . 2018 Dec; 47(5):629-644.e8. PMID: 30523786
Long-lived quiescent mammary stem cells (MaSCs) are presumed to coordinate the dramatic expansion of ductal epithelium that occurs through the different phases of postnatal development, but little is known about...
3.
Huynh N, Liu K, Yim M, Shulkes A, Baldwin G, He H
Physiol Rep . 2014 Jun; 2(6). PMID: 24963032
Gastrins, including amidated gastrin17 and glycine-extended gastrin17, are important growth factors in colorectal cancer (CRC). The p21-activated kinase 1 (PAK1) plays key roles in cellular processes including proliferation, survival, and...
4.
Liu K, Huynh N, Patel O, Shulkes A, Baldwin G, He H
Cancer Lett . 2013 Jul; 340(1):22-9. PMID: 23811286
P21 activated kinase 1 (PAK1) enhances colorectal cancer (CRC) progression by stimulating Wnt/β-catenin and Ras oncogene, which promote CRC survival via stimulation of hypoxia-inducible factor 1α (HIF-1α). The aim of...
5.
He H, Huynh N, Liu K, Malcontenti-Wilson C, Zhu J, Christophi C, et al.
Cancer Lett . 2011 Nov; 317(1):65-71. PMID: 22100495
The p21-activated kinase 1 (PAK1) plays important roles in cell growth, motility, and transformation. The aims of this study were to delineate the signalling mechanisms downstream of PAK1, and to...
6.
Huynh N, Liu K, Baldwin G, He H
Biochim Biophys Acta . 2010 Jul; 1803(9):1106-13. PMID: 20595063
The p21-activated kinase (PAK) family of serine/threonine kinases plays an important role in cell proliferation, survival and motility, as well as in cell transformation and tumor progression. PAK1 promotes transformation...
7.
He H, Yim M, Liu K, Cody S, Shulkes A, Baldwin G
Cell Signal . 2007 Oct; 20(1):83-93. PMID: 17936584
Gastrins, including amidated gastrin (Gamide) and glycine-extended gastrin (Ggly), are known to accelerate the growth of gastric and colorectal cancer cells by stimulation of proliferation and inhibition of apoptosis. Gamide...