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Kevin G Dsouza

Explore the profile of Kevin G Dsouza including associated specialties, affiliations and a list of published articles. Areas
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Citations 102
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Recent Articles
1.
Rehan M, Deskin B, Kurundkar A, Yadav S, Matsunaga Y, Manges J, et al.
J Biol Chem . 2023 Jul; 299(8):105027. PMID: 37423298
Metabolism controls cellular phenotype and fate. In this report, we demonstrate that nicotinamide N-methyltransferase (NNMT), a metabolic enzyme that regulates developmental stem cell transitions and tumor progression, is highly expressed...
2.
Dsouza K, Alexander A, Watts Jr J, Kulkarni T
Multidiscip Respir Med . 2023 May; 18(1):890. PMID: 37197388
Interstitial lung disease (ILD) is a common manifestation of systemic autoimmune diseases. A proportion of patients with autoimmune disease associated-ILDs develop progressive pulmonary fibrosis. Regular monitoring of patients with pulmonary...
3.
Dsouza K, Surolia R, Kulkarni T, Li F, Singh P, Zeng H, et al.
Respir Res . 2023 Mar; 24(1):96. PMID: 36978076
Background: Interstitial lung diseases (ILD) encompass a heterogenous group of diffuse parenchymal lung disorders characterized by variable degrees of inflammation and fibrosis. Pretherapeutic clinical testing models for such diseases can...
4.
Li F, Surolia R, Singh P, Dsouza K, Stephens C, Wang Z, et al.
Am J Physiol Lung Cell Mol Physiol . 2022 Feb; 322(4):L593-L606. PMID: 35200041
The etiologies of chronic obstructive pulmonary disease (COPD) remain unclear. Cadmium (Cd) causes both pulmonary fibrosis and emphysema; however, the predictors for Cd exposure and the mechanisms by which Cd...
5.
Kulkarni T, Valentine V, Fei F, Tran-Nguyen T, Quesada-Arias L, Mkorombindo T, et al.
PLoS One . 2021 Nov; 16(11):e0260345. PMID: 34813613
Background: No medical treatment has proven efficacy for acute exacerbations of idiopathic pulmonary fibrosis (AE-IPF), and this syndrome has a very high mortality. Based on data indicating humoral autoimmune processes...
6.
Chanda D, Rehan M, Smith S, Dsouza K, Wang Y, Bernard K, et al.
Elife . 2021 Sep; 10. PMID: 34528872
Multicellular organisms maintain structure and function of tissues/organs through emergent, self-organizing behavior. In this report, we demonstrate a critical role for lung mesenchymal stromal cell (L-MSC) aging in determining the...
7.
Rehan M, Kurundkar D, Kurundkar A, Logsdon N, Smith S, Chanda D, et al.
Nat Aging . 2021 Aug; 1(2):205-217. PMID: 34386777
Aging is a risk factor for progressive fibrotic disorders involving diverse organ systems, including the lung. Idiopathic pulmonary fibrosis, an age-associated degenerative lung disorder, is characterized by persistence of apoptosis-resistant...
8.
Surolia R, Li F, Wang Z, Kashyap M, Srivastava R, Traylor A, et al.
JCI Insight . 2021 May; 6(10). PMID: 34027893
Despite the high morbidity and mortality among patients with extensive cutaneous burns in the intensive care unit due to the development of acute respiratory distress syndrome, effective therapeutics remain to...
9.
Vijaykumar K, Dsouza K, Lerner L
J Bronchology Interv Pulmonol . 2017 Sep; 24(4):e60-e61. PMID: 28957899
No abstract available.
10.
Bennett J, Dsouza K, Patel M, ODwyer K
Leuk Res Rep . 2015 Feb; 4(1):12-4. PMID: 25709891
Chronic myelogenous leukemia (CML), in the Chronic Phase (CP), is often suspected as a result of a complete blood count (CBC), which shows increased granulocytes, mostly mature including a peak...