Kevin F Brulois
Overview
Explore the profile of Kevin F Brulois including associated specialties, affiliations and a list of published articles.
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18
Citations
1401
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Recent Articles
1.
Zhu Y, Xiang M, Brulois K, Lazarus N, Pan J, Butcher E
Res Sq
. 2024 Jul;
PMID: 38947054
Stromal cells within the tumor tissue promote immune evasion as a critical strategy for cancer development and progression, but the underlying mechanisms remain poorly understood. In this study, we explore...
2.
Paerregaard S, Wulff L, Schussek S, Niss K, Morbe U, Jendholm J, et al.
Nat Commun
. 2023 Apr;
14(1):2307.
PMID: 37085516
The intestinal lamina propria contains a diverse network of fibroblasts that provide key support functions to cells within their local environment. Despite this, our understanding of the diversity, location and...
3.
Zang R, Gomez Castro M, McCune B, Zeng Q, Rothlauf P, Sonnek N, et al.
Sci Immunol
. 2020 May;
5(47).
PMID: 32404436
Gastrointestinal symptoms and fecal shedding of SARS-CoV-2 RNA are frequently observed in COVID-19 patients. However, it is unclear whether SARS-CoV-2 replicates in the human intestine and contributes to possible fecal-oral...
4.
Ding S, Song Y, Brulois K, Pan J, Co J, Ren L, et al.
Gastroenterology
. 2020 Apr;
159(1):214-226.e1.
PMID: 32247021
Background & Aims: Intestinal microfold (M) cells are a unique subset of intestinal epithelial cells in the Peyer's patches that regulate mucosal immunity, serving as portals for sampling and uptake...
5.
Ding S, Diep J, Feng N, Ren L, Li B, Ooi Y, et al.
Nat Commun
. 2018 Apr;
9(1):1485.
PMID: 29662124
Cohesin is a multi-subunit nuclear protein complex that coordinates sister chromatid separation during cell division. Highly frequent somatic mutations in genes encoding core cohesin subunits have been reported in multiple...
6.
Liang Q, Wei D, Chung B, Brulois K, Guo C, Dong S, et al.
J Virol
. 2017 Nov;
92(4).
PMID: 29167347
The viral Bcl-2 homolog (vBcl2) of Kaposi's sarcoma-associated herpesvirus (KSHV) displays efficient antiapoptotic and antiautophagic activity through its central BH3 domain, which functions to prolong the life span of virus-infected...
7.
Zhang Z, Chen W, Sanders M, Brulois K, Dittmer D, Damania B
J Virol
. 2016 Jun;
90(17):7657-66.
PMID: 27307571
Unlabelled: The K1 gene product of Kaposi's sarcoma-associated herpesvirus (KSHV) is encoded by the first open reading frame (ORF) of the viral genome. To investigate the role of the K1...
8.
Nicol S, Sabbah S, Brulois K, Jung J, Bell A, Hislop A
J Virol
. 2016 Jan;
90(8):3849-3859.
PMID: 26819313
Unlabelled: Kaposi's sarcoma-associated herpesvirus (KSHV) has tropism for B lymphocytes, in which it establishes latency, and can also cause lymphoproliferative disorders of these cells manifesting as primary effusion lymphoma (PEL)...
9.
Liang Q, Chang B, Lee P, Brulois K, Ge J, Shi M, et al.
J Virol
. 2015 Mar;
89(10):5308-17.
PMID: 25740994
Unlabelled: Kaposi's sarcoma-associated herpesvirus (KSHV) evades host defenses through tight suppression of autophagy by targeting each step of its signal transduction: by viral Bcl-2 (vBcl-2) in vesicle nucleation, by viral...
10.
Gelgor A, Kalt I, Bergson S, Brulois K, Jung J, Sarid R
J Virol
. 2015 Mar;
89(10):5298-307.
PMID: 25740992
Unlabelled: The Kaposi's sarcoma-associated herpesvirus (KSHV) open reading frame 16 (orf16) encodes a viral Bcl-2 (vBcl-2) protein which shares sequence and functional homology with the Bcl-2 family. Like its cellular...