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Kevin B Vargo

Explore the profile of Kevin B Vargo including associated specialties, affiliations and a list of published articles. Areas
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Articles 10
Citations 145
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Recent Articles
1.
OCallaghan J, Kamat N, Vargo K, Chattaraj R, Lee D, Hammer D
Eur Phys J E Soft Matter . 2024 Jun; 47(6):37. PMID: 38829453
In this study, we demonstrate the fabrication of polymersomes, protein-blended polymersomes, and polymeric microcapsules using droplet microfluidics. Polymersomes with uniform, single bilayers and controlled diameters are assembled from water-in-oil-in-water double-emulsion...
2.
Vargo K, Stahl P, Hwang B, Hwang E, Giordano D, Randolph P, et al.
Mol Pharm . 2020 Nov; 18(1):148-157. PMID: 33253579
Biological drug products are formulated with excipients to maintain stability over the shelf life of the product. Surfactants are added to the drug product to stabilize air-water interfaces known to...
3.
Gao C, Vargo K, Hammer D
Macromol Biosci . 2016 Jun; 16(9):1398-406. PMID: 27284959
Targeting nanoparticles for drug delivery has great potential for improving efficacy and reducing side effects from systemic toxicity. New developments in the assembly of materials afford the opportunity to expose...
4.
Griepenburg J, Sood N, Vargo K, Williams D, Rawson J, Therien M, et al.
Langmuir . 2014 Dec; 31(2):799-807. PMID: 25518002
Polymersomes are bilayer vesicles that self-assemble from amphiphilic diblock copolymers, and provide an attractive system for the delivery of biological and nonbiological molecules due to their environmental compatibility, mechanical stability,...
5.
Vargo K, Al Zaki A, Warden-Rothman R, Tsourkas A, Hammer D
Small . 2014 Nov; 11(12):1409-13. PMID: 25418741
Recombinant surfactants present a new platform for stabilizing and targeting nanoparticle imaging agents. Superparamagnetic iron oxide nanoparticle-loaded micelles for MRI contrast are stabilized by an engineered variant of the naturally...
6.
McDaniel J, Weitzhandler I, Prevost S, Vargo K, Appavou M, Hammer D, et al.
Nano Lett . 2014 Oct; 14(11):6590-8. PMID: 25268037
Elastin-like polypeptides (ELPs) are a class of biopolymers consisting of the pentameric repeat (VPGαG)n based on the sequence of mammalian tropoelastin that display a thermally induced soluble-to-insoluble phase transition in...
7.
Angile F, Vargo K, Sehgal C, Hammer D, Lee D
Langmuir . 2014 Sep; 30(42):12610-8. PMID: 25265041
Microbubbles are used as contrast enhancing agents in ultrasound sonography and more recently have shown great potential as theranostic agents that enable both diagnostics and therapy. Conventional production methods lead...
8.
Vargo K, Sood N, Moeller T, Heiney P, Hammer D
Langmuir . 2014 Aug; 30(38):11292-300. PMID: 25145981
An emerging field in biomaterials is the creation and engineering of protein surfactants made by recombinant biotechnology. Protein surfactants made by recombinant biotechnology allow for complete control of the molecular...
9.
McDaniel J, Bhattacharyya J, Vargo K, Hassouneh W, Hammer D, Chilkoti A
Angew Chem Int Ed Engl . 2013 Jan; 52(6):1683-7. PMID: 23280697
No abstract available.
10.
Vargo K, Parthasarathy R, Hammer D
Proc Natl Acad Sci U S A . 2012 Jul; 109(29):11657-62. PMID: 22753512
Using recombinant amphiphilic proteins to self-assemble suprastructures would allow precise control over surfactant chemistry and the facile incorporation of biological functionality. We used cryo-TEM to confirm self-assembled structures from recombinantly...