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Kevan Jacobson

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Articles 136
Citations 2634
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Recent Articles
1.
Aziz B, Belaghi R, Huynh H, Jacobson K, Mack D, Deslandres C, et al.
Clin Transl Gastroenterol . 2025 Jan; PMID: 39835685
Introduction: Neutrophil-to-lymphocyte ratio (NLR) is a novel biomarker studied in several autoimmune diseases including inflammatory bowel disease (IBD) in adults but poorly characterized in pediatric IBD (pIBD). We aimed to...
2.
Kantham S, Yu H, Cantelli C, Chen G, Ma C, Chan J, et al.
Bioorg Med Chem Lett . 2025 Jan; 119:130093. PMID: 39793629
Prostaglandin E receptor type 4 (EP4) agonists have been shown to be effective in treating experimental ulcerative colitis (UC) in animals and in human clinical trials, but their development has...
3.
Ford M, Iuliano A, Walters T, Otley A, Mack D, Jacobson K, et al.
Health Care Transit . 2024 Dec; 3:100085. PMID: 39712477
Background: Inflammatory bowel disease (IBD) is a chronic autoimmune disease often diagnosed during adolescence. IBD negatively impacts all aspects of health-related quality of life, resulting in physical, emotional, social, school,...
4.
Lee S, Bushra M, Qiu L, Shao J, Olivera P, Leibovitzh H, et al.
Gastroenterology . 2024 Oct; 168(2):385-388.e3. PMID: 39384162
No abstract available.
5.
Olivera P, Martinez-Lozano H, Leibovitzh H, Xue M, Neustaeter A, Espin-Garcia O, et al.
Gastroenterology . 2024 Sep; 168(1):99-110.e2. PMID: 39236898
Background & Aims: Unaffected first-degree relatives (FDRs) from families with ≥2 affected FDRs with Crohn's disease (CD, multiplex families) have a high risk of developing CD, although the underlying mechanisms...
6.
Chen B, Hamilton Z, Hasosah M, Zetler P, Popescu O, Bush J, et al.
Am J Clin Pathol . 2024 Jun; PMID: 38934570
Objectives: Upper gastrointestinal (UGI) tract involvement is frequently reported in pediatric Crohn disease (CD) and ulcerative colitis (UC). Aside from granulomas, most findings are nonspecific. The aims of this study...
7.
Kennedy A, Griffiths A, Muise A, Walters T, Ricciuto A, Huynh H, et al.
Inflamm Bowel Dis . 2024 May; 30(12):2418-2427. PMID: 38788739
Background: Patients with inflammatory bowel disease (IBD) exhibit considerable interindividual variability in medication response, highlighting the need for precision medicine approaches to optimize and tailor treatment. Pharmacogenetics (PGx) offers the...
8.
Dijk S, Jarman M, Zhang Z, Lawley M, Ahmad M, Suarez R, et al.
Nutrients . 2024 Apr; 16(7). PMID: 38613066
Exclusive enteral nutrition (EEN) is effective in inducing remission in pediatric Crohn disease (CD). EEN alters the intestinal microbiome, but precise mechanisms are unknown. We hypothesized that pre-diagnosis diet establishes...
9.
Kuenzig M, Stukel T, Carroll M, Kaplan G, Otley A, Singh H, et al.
Clin Epidemiol . 2024 Feb; 16:91-108. PMID: 38374886
Purpose: The incidence of childhood-onset inflammatory bowel disease (IBD) is rising. We described variation in health services utilization and need for surgery among children with IBD between six and 60...
10.
Kuenzig M, Bitton A, Carroll M, Otley A, Singh H, Kaplan G, et al.
Inflamm Bowel Dis . 2024 Feb; 30(12):2356-2369. PMID: 38366807
Background: Patterns of health services utilization among children with inflammatory bowel disease (IBD) are important to understand as the number of children with IBD continues to increase. We compared health...