Keun Ah Ryu
Overview
Explore the profile of Keun Ah Ryu including associated specialties, affiliations and a list of published articles.
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Snapshot
Snapshot
Articles
18
Citations
338
Followers
0
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Related Specialties
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Top 10 Co-Authors
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Recent Articles
1.
Datta S, Chen D, Tavares A, Reyes-Robles T, Ryu K, Khan N, et al.
Cell Chem Biol
. 2023 Jul;
30(10):1313-1322.e7.
PMID: 37499664
Identifying virus-host interactions on the cell surface can improve our understanding of viral entry and pathogenesis. SARS-CoV-2, the causative agent of the COVID-19 disease, uses ACE2 as a receptor to...
2.
Huth S, Oakley J, Seath C, Jacob B Geri , Trowbridge A, Parker Jr D, et al.
J Am Chem Soc
. 2023 Jul;
145(30):16289-16296.
PMID: 37471577
The characterization of ligand binding modes is a crucial step in the drug discovery process and is especially important in campaigns arising from phenotypic screening, where the protein target and...
3.
Hope T, Reyes-Robles T, Ryu K, Mauries S, Removski N, Maisonneuve J, et al.
Chem Sci
. 2023 Jul;
14(26):7327-7333.
PMID: 37416718
Flavin-based photocatalysts such as riboflavin tetraacetate (RFT) serve as a robust platform for light-mediated protein labelling phenoxy radical-mediated tyrosine-biotin phenol coupling on live cells. To gain insight into this coupling...
4.
Kawamata Y, Ryu K, Hermann G, Sandahl A, Vantourout J, Olow A, et al.
Nat Chem
. 2023 Jun;
15(9):1267-1275.
PMID: 37322100
Target identification involves deconvoluting the protein target of a pharmacologically active, small-molecule ligand, a process that is critical for early drug discovery yet technically challenging. Photoaffinity labelling strategies have become...
5.
Ryu K, Kaszuba C, Bissonnette N, Oslund R, Fadeyi O
Nat Rev Chem
. 2023 Apr;
5(5):322-337.
PMID: 37117838
Light-powered catalysis has found broad utility as a chemical transformation strategy, with widespread impact on energy, environment, drug discovery and human health. A noteworthy application impacting human health is light-induced...
6.
Soon Tay N, Ryu K, Weber J, Olow A, Cabanero D, Reichman D, et al.
Nat Chem
. 2022 Oct;
15(1):101-109.
PMID: 36216892
State-of-the-art photoactivation strategies in chemical biology provide spatiotemporal control and visualization of biological processes. However, using high-energy light (λ < 500 nm) for substrate or photocatalyst sensitization can lead to...
7.
Trowbridge A, Seath C, Rodriguez-Rivera F, Li B, Dul B, Schwaid A, et al.
Proc Natl Acad Sci U S A
. 2022 Aug;
119(34):e2208077119.
PMID: 35969791
Over half of new therapeutic approaches fail in clinical trials due to a lack of target validation. As such, the development of new methods to improve and accelerate the identification...
8.
Bissonnette N, Ryu K, Reyes-Robles T, Wilhelm S, Tomlinson J, Crotty K, et al.
Chembiochem
. 2020 Aug;
21(24):3555-3562.
PMID: 32749732
Despite the growing use of visible-light photochemistry in both chemistry and biology, no general low-heat photoreactor for use across these different disciplines exists. Herein, we describe the design and use...
9.
Ryu K, McGonnigal B, Moore T, Kargupta T, Mancini R, Esser-Kahn A
Sci Rep
. 2017 Aug;
7(1):8074.
PMID: 28808328
The complexity of the immune system creates challenges in exploring its importance and robustness. To date, there have been few techniques developed to manipulate individual components of the immune system...
10.
Lybaert L, Ryu K, De Rycke R, Chon A, de Wever O, Vermaelen K, et al.
Adv Sci (Weinh)
. 2017 Jun;
4(6):1700050.
PMID: 28638786
Targeting the immune system with a personalized vaccine containing cues derived from the patient's malignancy might be a promising approach in the fight against cancer. It includes neo-antigens as well...