Kessler McCoy-Simandle
Overview
Explore the profile of Kessler McCoy-Simandle including associated specialties, affiliations and a list of published articles.
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Articles
8
Citations
381
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Recent Articles
1.
Hanna S, McCoy-Simandle K, Leung E, Genna A, Condeelis J, Cox D
J Cell Sci
. 2019 Jan;
132(3).
PMID: 30659112
The interaction between tumor cells and macrophages is crucial in promoting tumor invasion and metastasis. In this study, we examined a novel mechanism of intercellular communication, namely membranous actin-based tunneling...
2.
Hanna S, McCoy-Simandle K, Miskolci V, Guo P, Cammer M, Hodgson L, et al.
Sci Rep
. 2017 Aug;
7(1):8547.
PMID: 28819224
Macrophage interactions with other cells, either locally or at distances, are imperative in both normal and pathological conditions. While soluble means of communication can transmit signals between different cells, it...
3.
Mallama C, McCoy-Simandle K, Cianciotto N
Infect Immun
. 2017 Feb;
85(4).
PMID: 28138020
Previously, we reported that mutants of lacking a type II secretion (T2S) system elicit higher levels of cytokines (e.g., interleukin-6 [IL-6]) following infection of U937 cells, a human macrophage-like cell...
4.
McCoy-Simandle K, Hanna S, Cox D
Int J Biochem Cell Biol
. 2015 Dec;
71:44-54.
PMID: 26704468
Cell-cell communication is critical to coordinate the activity and behavior of a multicellular organism. The cells of the immune system not only must communicate with similar cells, but also with...
5.
McCoy-Simandle K, Stewart C, Dao J, DebRoy S, Rossier O, Bryce P, et al.
Infect Immun
. 2011 Mar;
79(5):1984-97.
PMID: 21383054
The type II secretion (T2S) system of Legionella pneumophila is required for the ability of the bacterium to grow within the lungs of A/J mice. By utilizing mutants lacking T2S...
6.
Allard K, Dao J, Sanjeevaiah P, McCoy-Simandle K, Chatfield C, Crumrine D, et al.
Infect Immun
. 2009 Apr;
77(7):2887-95.
PMID: 19398549
When cultured in a low-iron medium, Legionella pneumophila secretes a siderophore (legiobactin) that is both reactive in the chrome azurol S (CAS) assay and capable of stimulating the growth of...
7.
Himmel D, Sarafianos S, Dharmasena S, Hossain M, McCoy-Simandle K, Ilina T, et al.
ACS Chem Biol
. 2006 Dec;
1(11):702-12.
PMID: 17184135
The rapid emergence of drug-resistant variants of human immunodeficiency virus, type 1 (HIV-1), has limited the efficacy of anti-acquired immune deficiency syndrome (AIDS) treatments, and new lead compounds that target...
8.
Soares R, Barron T, McCoy-Simandle K, Svobodova M, Warburg A, Turco S
Exp Parasitol
. 2004 Jun;
107(1-2):105-14.
PMID: 15208044
Lipophosphoglycan (LPG) is a dominant surface molecule of Leishmania promastigotes which has been shown to be critical for parasite-sand fly vector interactions. To provide additional evidence for its importance in...