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Kerstin Fuchs

Explore the profile of Kerstin Fuchs including associated specialties, affiliations and a list of published articles. Areas
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Articles 29
Citations 364
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Recent Articles
1.
Cotton J, Goehring C, Kuehn A, Maurer A, Fuchs K, Pichler B
Pharmaceuticals (Basel) . 2021 Aug; 14(8). PMID: 34451843
The acidic hydrolase α-fucosidase (AF) is a biomarker for maladies such as cancer and inflammation. The most advanced probes for α-fucosidase are unfortunately constrained to ex vivo or in vitro...
2.
Neveu M, Beziere N, Daniels R, Bouzin C, Comment A, Schwenck J, et al.
Mol Imaging Biol . 2020 Jun; 22(5):1324-1332. PMID: 32514887
Purpose: Inflammation is involved in many disease processes. However, accurate imaging tools permitting diagnosis and characterization of inflammation are still missing. As inflamed tissues exhibit a high rate of glycolysis,...
3.
Hoffmann S, Reck D, Maurer A, Fehrenbacher B, Sceneay J, Poxleitner M, et al.
Theranostics . 2019 Sep; 9(20):5869-5885. PMID: 31534525
Myeloid-derived suppressor cells (MDSCs) are immunosuppressive cells of the myeloid compartment and major players in the tumor microenvironment (TME). With increasing numbers of studies describing MDSC involvement in cancer immune...
4.
Steimle A, Michaelis L, Di Lorenzo F, Kliem T, Munzner T, Maerz J, et al.
Mol Ther . 2019 Aug; 27(11):1974-1991. PMID: 31416777
Generated by gram-negative bacteria, lipopolysaccharides (LPSs) are one of the most abundant and potent immunomodulatory substances present in the intestinal lumen. Interaction of agonistic LPS with the host myeloid-differentiation-2/Toll-like receptor...
5.
Schwenck J, Maurer A, Fehrenbacher B, Mehling R, Knopf P, Mucha N, et al.
Theranostics . 2019 Jul; 9(13):3903-3917. PMID: 31281521
Cysteine-type cathepsins such as cathepsin B are involved in various steps of inflammatory processes such as antigen processing and angiogenesis. Here, we uncovered the role of cysteine-type cathepsins in the...
6.
Beziere N, Fuchs K, Maurer A, Reischl G, Bruck J, Ghoreschi K, et al.
Theranostics . 2019 Jun; 9(10):2868-2881. PMID: 31244929
In a variety of diseases, from benign to life-threatening ones, inflammation plays a major role. Monitoring the intensity and extent of a multifaceted inflammatory process has become a cornerstone in...
7.
Guenthoer P, Fuchs K, Reischl G, Quintanilla-Martinez L, Gonzalez-Menendez I, Laufer S, et al.
Inflammopharmacology . 2019 May; 27(6):1217-1227. PMID: 31037574
Background: Mitogen-activated protein kinase (MAPK) signaling plays an important role in inflammatory diseases such as rheumatoid arthritis (RA).The aim of our study was to elucidate the therapeutic potential of the...
8.
Maier F, Wild A, Kirchen N, Holm F, Fuchs K, Schwenck J, et al.
Appl Radiat Isot . 2018 Nov; 143:149-155. PMID: 30445280
Here, we describe immuno-Cerenkov luminescence imaging (immuno-CLI) with a specific monoclonal antibody-based tracer for the detection of prostate tumors, which is used in preclinical positron emission tomography (PET) imaging. As...
9.
Pohl J, Volke J, Thiebes S, Brenzel A, Fuchs K, Beziere N, et al.
Eur J Immunol . 2018 Feb; 48(6):990-1000. PMID: 29446073
The hemolytic uremic syndrome (HUS) is a life-threatening disease of the kidney that is induced by shiga toxin-producing E.coli. Major changes in the monocytic compartment and in CCR2-binding chemokines have...
10.
Mannheim J, Kara F, Doorduin J, Fuchs K, Reischl G, Liang S, et al.
Mol Imaging Biol . 2017 Oct; 20(5):716-731. PMID: 28971332
The benefit of small animal imaging is directly linked to the validity and reliability of the collected data. If the data (regardless of the modality used) are not reproducible and/or...