Kerstin Cornils
Overview
Explore the profile of Kerstin Cornils including associated specialties, affiliations and a list of published articles.
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35
Citations
919
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Recent Articles
1.
Prasse N, Wessolowski C, Muller I, Cornils K, Franke A
Int J Mol Sci
. 2024 May;
25(10).
PMID: 38791381
Osteosarcoma is a type of bone cancer that primarily affects children and young adults. The overall 5-year survival rate for localized osteosarcoma is 70-75%, but it is only 20-30% for...
2.
Alhaj Hussen K, Chabaane E, Nelson E, Lekiashvili S, Diop S, Keita S, et al.
iScience
. 2023 Sep;
26(10):107890.
PMID: 37766969
The developmental cartography of human lymphopoiesis remains incompletely understood. Here, we establish a multimodal map demonstrating that lymphoid specification follows independent direct or stepwise hierarchic routes converging toward the emergence...
3.
Franke A, Wessolowski C, Thaden V, Muller I, Cornils K
Gene Ther
. 2022 Dec;
30(7-8):603-611.
PMID: 36529796
In the last decade, treatment using Chimeric Antigen Receptor (CAR) are largely studied and demonstrate the potential of immunotherapeutic strategies, as seen mainly for blood related cancers. Still, efficient CAR-T...
4.
Schutze K, Gross M, Cornils K, Wustrau K, Schneppenheim S, Lenhartz H, et al.
Blood Adv
. 2022 Oct;
7(8):1531-1535.
PMID: 36206192
Most hereditary forms of hemophagocytic lymphohistiocytosis (HLH) are caused by defects of cytotoxicity, including the vesicle trafficking disorder Griscelli syndrome type 2 (GS2, RAB27A deficiency). Deficiency of the mitogen-activated protein...
5.
Hageb A, Thalheim T, Nattamai K, Mohrle B, Sacma M, Sakk V, et al.
Life Sci Alliance
. 2022 Apr;
5(8).
PMID: 35487692
Upon aging, the function of the intestinal epithelium declines with a concomitant increase in aging-related diseases. ISCs play an important role in this process. It is known that ISC clonal...
6.
Gotzhein F, Aranyossy T, Thielecke L, Sonntag T, Thaden V, Fehse B, et al.
Int J Mol Sci
. 2022 Mar;
23(6).
PMID: 35328579
Hematopoietic stem cell transplantation (HSCT) represents the only curative treatment option for numerous hematologic malignancies. While the influence of donor age and the composition of the graft have already been...
7.
Thielecke L, Cornils K, Glauche I
Bioinformatics
. 2019 Nov;
36(7):2189-2194.
PMID: 31782763
Motivation: Genetic barcodes have been established as an efficient method to trace clonal progeny of uniquely labeled cells by introducing artificial genetic sequences into the corresponding genomes. The assessment of...
8.
Velthaus A, Cornils K, Hennigs J, Grub S, Stamm H, Wicklein D, et al.
Cancers (Basel)
. 2019 Nov;
11(11).
PMID: 31717802
Leukemia-initiating cells reside within the bone marrow in specialized niches where they undergo complex interactions with their surrounding stromal cells. We have identified the actin-binding protein Plastin-3 (PLS3) as potential...
9.
Shemer A, Grozovski J, Tay T, Tao J, Volaski A, Suss P, et al.
Nat Commun
. 2018 Dec;
9(1):5206.
PMID: 30523248
Microglia are yolk sac-derived macrophages residing in the parenchyma of brain and spinal cord, where they interact with neurons and other glial. After different conditioning paradigms and bone marrow (BM)...
10.
Roh V, Abramowski P, Hiou-Feige A, Cornils K, Rivals J, Zougman A, et al.
Cell Rep
. 2018 Nov;
25(8):2208-2222.e7.
PMID: 30463016
Local recurrence after surgery for head and neck squamous cell carcinoma (HNSCC) remains a common event associated with a dismal prognosis. Improving this outcome requires a better understanding of cancer...