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Kerry S Wadey

Explore the profile of Kerry S Wadey including associated specialties, affiliations and a list of published articles. Areas
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Articles 7
Citations 37
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Recent Articles
1.
Wadey K, Somos A, Leyden G, Blythe H, Chan J, Hutchinson L, et al.
Front Cardiovasc Med . 2023 Feb; 9:1059124. PMID: 36794234
Background: Endothelial dysfunction is a critical component of both atherosclerotic plaque formation and saphenous vein graft failure. Crosstalk between the pro-inflammatory TNF-α-NFκB signaling axis and the canonical Wnt/β-catenin signaling pathway...
2.
Wadey K, Johnson J, George S
Methods Mol Biol . 2022 Mar; 2419:507-519. PMID: 35237985
Immunohistochemistry for specific proteins characteristic of proliferative or apoptotic cells allows for monitoring of these cell behaviors in biological tissues samples, including atherosclerotic plaques and intimal thickenings. Proliferating cell nuclear...
3.
Wadey K, Somos A, Cross S, Reolizo L, Johnson J, George S
Methods Mol Biol . 2022 Mar; 2419:133-167. PMID: 35237963
Bromodeoxyuridine/5-bromo-2'-deoxyuridine (BrdU) is a nucleoside analog of thymidine and its incorporation into DNA during replication within S-phase of the cell cycle is used to quantify cell proliferation. Quantification of incorporated...
4.
Williams H, Wadey K, Frankow A, Blythe H, Forbes T, Johnson J, et al.
J Cell Commun Signal . 2021 Jun; 15(3):421-432. PMID: 34080128
Patients with abdominal aortic aneurysms are frequently treated with high-risk surgery. A pharmaceutical treatment to reverse aneurysm progression could prevent the need for surgery and save both lives and healthcare...
5.
Lyon C, Williams H, Bianco R, Simmonds S, Brown B, Wadey K, et al.
Sci Rep . 2017 Dec; 7(1):17342. PMID: 29229950
There is an unmet need for treatments to reduce abdominal aortic aneurysm (AAA) progression. Vascular smooth muscle cell (VSMC) apoptosis precipitates AAA formation, whereas VSMC proliferation repairs the vessel wall....
6.
Hulin-Curtis S, Williams H, Wadey K, Sala-Newby G, George S
Mol Ther Methods Clin Dev . 2017 May; 5:191-199. PMID: 28540322
Approximately 50% of coronary artery bypass grafts using the autologous saphenous vein fail within 10 years due to intimal thickening. This study examined whether a gene therapy approach that selectively...
7.
Lyon C, Wadey K, George S
Vascul Pharmacol . 2015 Nov; 78:53-62. PMID: 26586312
Reoccurrence of symptoms occurs in 30-50% of coronary artery disease patients receiving vein grafts or bare-metal stents due to intimal thickening (restenosis). Restenosis is caused by vascular smooth muscle cell...