Kennichi Dowdell
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Explore the profile of Kennichi Dowdell including associated specialties, affiliations and a list of published articles.
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Articles
17
Citations
183
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Recent Articles
1.
Wang K, Jordan T, Dowdell K, Herbert R, Moore I, Koelle D, et al.
PLoS Pathog
. 2024 Sep;
20(9):e1012477.
PMID: 39226323
The most commonly used animal models for evaluating the efficacy of HSV-2 candidate vaccines are mice and guinea pigs. While numerous HSV-2 vaccine candidates have been tested in these animals...
2.
Kaiser J, Nelson C, Liu X, Park H, Matsuoka Y, Luongo C, et al.
Nat Commun
. 2024 Apr;
15(1):3553.
PMID: 38670948
Immunization via the respiratory route is predicted to increase the effectiveness of a SARS-CoV-2 vaccine. Here, we evaluate the immunogenicity and protective efficacy of one or two doses of a...
3.
Bu W, Kumar A, Board N, Kim J, Dowdell K, Zhang S, et al.
Immunity
. 2024 Mar;
57(3):559-573.e6.
PMID: 38479361
Epstein-Barr virus (EBV) causes infectious mononucleosis and is associated with B cell lymphomas. EBV glycoprotein 42 (gp42) binds HLA class II and activates membrane fusion with B cells. We isolated...
4.
Buchholz U, Kaiser J, Nelson C, Liu X, Park H, Matsuoka Y, et al.
Res Sq
. 2023 Oct;
PMID: 37790295
Immunization via the respiratory route is predicted to increase the effectiveness of a SARS-CoV-2 vaccine. We evaluated the immunogenicity and protective efficacy of one or two doses of a live-attenuated...
5.
Melani C, Dowdell K, Pittaluga S, Dunleavy K, Roschewski M, Song J, et al.
Lancet Haematol
. 2023 Apr;
10(5):e346-e358.
PMID: 37011643
Background: Lymphomatoid granulomatosis is a rare Epstein-Barr virus-associated B-cell lymphoproliferative disorder with a median overall survival of less than 2 years. In this study, we hypothesised that low-grade lymphomatoid granulomatosis...
6.
Brault J, Liu T, Bello E, Liu S, Sweeney C, Meis R, et al.
Blood
. 2021 Jun;
138(26):2768-2780.
PMID: 34086870
XMEN disease, defined as "X-linked MAGT1 deficiency with increased susceptibility to Epstein-Barr virus infection and N-linked glycosylation defect," is a recently described primary immunodeficiency marked by defective T cells and...
7.
Wang K, Dropulic L, Bozekowski J, Pietz H, Jegaskanda S, Dowdell K, et al.
J Infect Dis
. 2021 Mar;
224(9):1509-1519.
PMID: 33718970
Previous herpes simplex virus type 2 (HSV-2) vaccines have not prevented genital herpes. Concerns have been raised about the choice of antigen, the type of antibody induced by the vaccine,...
8.
Brault J, Meis R, Li L, Bello E, Liu T, Sweeney C, et al.
Cytotherapy
. 2020 Oct;
23(3):203-210.
PMID: 33051095
Background Aim: X-linked MAGT1 deficiency with increased susceptibility to EBV-infection and N-linked glycosylation defect' (XMEN) disease is caused by mutations in the magnesium transporter 1 (MAGT1) gene. Loss of MAGT1...
9.
Howe M, Dowdell K, Kuehn H, Li Q, Hart G, Garabedian D, et al.
J Infect Dis
. 2020 May;
222(7):1170-1179.
PMID: 32386415
Background: Chronic active Epstein-Barr virus (CAEBV) presents with high levels of viral genomes in blood and tissue infiltration with Epstein-Barr virus (EBV)-positive lymphocytes. The pathogenesis of CAEBV is poorly understood....
10.
Howe M, Dowdell K, Roy A, Niemela J, Wilson W, McElwee J, et al.
Front Immunol
. 2019 Sep;
10:2000.
PMID: 31507602
Interleukin-2-inducible T cell kinase (ITK) is critical for T cell signaling and cytotoxicity, and control of Epstein-Barr virus (EBV). We identified a patient with a novel homozygous missense mutation (D540N)...