Kenneth R Wagner
Overview
Explore the profile of Kenneth R Wagner including associated specialties, affiliations and a list of published articles.
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23
Citations
796
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Recent Articles
1.
Adeoye O, Clark J, Khatri P, Wagner K, Zuccarello M, Pyne-Geithman G
Transl Stroke Res
. 2013 Dec;
2(1):17-25.
PMID: 24323583
Although intracerebral hemorrhage (ICH) has no proven treatment, well-designed studies using animal models of ICH may lead to the development of novel therapies. We briefly review current animal models of...
2.
Suofu Y, Clark J, Broderick J, Wagner K, Tomsick T, Sa Y, et al.
J Neurochem
. 2010 Oct;
115(5):1266-76.
PMID: 20883517
Matrix metalloproteinases (MMPs) play an important role in reperfusion-induced brain injury following ischemia. To define the effects of peroxynitrite decomposition catalyst on MMP activation and neurovascular reperfusion injury, 5,10,15,20-tetrakis (2,4,6-trimethyl-3,5-disulfonatophenyl)-porphyrin...
3.
Lu A, Clark J, Broderick J, Pyne-Geithman G, Wagner K, Khatri P, et al.
Exp Neurol
. 2009 Jan;
216(2):407-12.
PMID: 19162014
A major complication of recanalization therapy after an acute arterial occlusion in brain is hemorrhagic transformation (HT). Although it is known that prolonged ischemia is important in the development of...
4.
Lu A, Clark J, Ran R, Pyne-Geithman G, Wagner K, Millhorn D, et al.
Neurol Res
. 2008 Dec;
31(5):545-9.
PMID: 19055876
Objective: The discovery of IL-7R(alpha) polymorphisms implicated in the pathogenesis of multiple sclerosis has highlighted the importance of interleukin 7 (IL-7) in central nervous system diseases. Hypoxia affects neurological disease...
5.
Xu H, Tang Y, Liu D, Ran R, Ander B, Apperson M, et al.
J Cereb Blood Flow Metab
. 2008 Apr;
28(7):1320-8.
PMID: 18382470
There are no biomarkers that differentiate cardioembolic from large-vessel atherosclerotic stroke, although the treatments differ for each and approximately 30% of strokes and transient ischemic attacks have undetermined etiologies using...
6.
Lu A, Clark J, Broderick J, Pyne-Geithman G, Wagner K, Ran R, et al.
Exp Neurol
. 2008 Jan;
210(2):549-59.
PMID: 18187134
In this study, we examine the effects of reperfusion on the activation of matrix metalloproteinase (MMP) and assess the relationship between MMP activation during reperfusion and neurovascular injury. Ischemia was...
7.
Loftspring M, Clark J, Wagner K
Brain Res
. 2007 Jul;
1162:130-2.
PMID: 17618608
We have developed a novel type of duplex enzyme-linked immunosorbent assay (ELISA) for the quantitation of the major plasma proteins, IgG and albumin, in edematous brain tissue. We test this...
8.
Shaw G, Dhamija A, Bavani N, Wagner K, Holland C
Phys Med Biol
. 2007 May;
52(11):2953-67.
PMID: 17505082
Stroke is a devastating disease and a leading cause of death and disability. Currently, the only FDA approved therapy for acute ischemic stroke is the intravenous administration of the thrombolytic...
9.
Wagner K
Stroke
. 2007 Jan;
38(2 Suppl):753-8.
PMID: 17261732
A significant amount of new information has been generated in animal models of intracerebral hemorrhage during the past several years. These include findings on the pathophysiological, biochemical and molecular processes...
10.
Loftspring M, Beiler S, Beiler C, Wagner K
J Neurotrauma
. 2006 Dec;
23(12):1904-11.
PMID: 17184198
Intracerebral hemorrhage (ICH) and traumatic brain injury can induce brain tissue edema (i.e., interstitial and/or vasogenic), containing high concentrations of plasma proteins. To understand biochemical processes in edema development following...