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Kenneth L Kramer

Explore the profile of Kenneth L Kramer including associated specialties, affiliations and a list of published articles. Areas
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Articles 16
Citations 363
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Recent Articles
1.
Giffen K, Liu H, Yamane K, Li Y, Chen L, Kramer K, et al.
Front Neurol . 2024 Nov; 15:1437558. PMID: 39484049
Introduction: Hair cells (HCs) are the sensory receptors of the auditory and vestibular systems in the inner ears of vertebrates that selectively transduce mechanical stimuli into electrical activity. Although all...
2.
Baker C, Marta A, Zimmerman N, Korade Z, Mathy N, Wilton D, et al.
Biomolecules . 2024 Aug; 14(8). PMID: 39199302
Carnitine palmitoyltransferase 2 (CPT2) is an inner mitochondrial membrane protein of the carnitine shuttle and is involved in the beta-oxidation of long chain fatty acids. Beta-oxidation provides an alternative pathway...
3.
Keim S, Harmon D, Martindale J, Lopez E, Sanky C, Brooks W, et al.
Anat Sci Educ . 2023 Mar; 16(5):943-957. PMID: 36929575
Clerkships are defining experiences for medical students in which students integrate basic science knowledge with clinical information as they gain experience in diagnosing and treating patients in a variety of...
4.
Spead O, Moreland T, Weaver C, Dalla Costa I, Hegarty B, Kramer K, et al.
Cell Rep . 2023 Mar; 42(3):112192. PMID: 36857189
Building precise neural circuits necessitates the elimination of axonal projections that have inaccurately formed during development. Although axonal pruning is a selective process, how it is initiated and controlled in ...
5.
Giffen K, Liu H, Kramer K, He D
Front Neurosci . 2019 Nov; 13:1117. PMID: 31680844
Non-mammalian vertebrates, including zebrafish, retain the ability to regenerate hair cells (HCs) due to unknown molecular mechanisms that regulate proliferation and conversion of non-sensory supporting cells (nsSCs) to HCs. This...
6.
Thiessen K, Grzegorski S, Chin Y, Higuchi L, Wilkinson C, Shavit J, et al.
Mech Dev . 2019 Apr; 157:1-9. PMID: 30974150
Deflecting biomineralized crystals attached to vestibular hair cells are necessary for maintaining balance. Zebrafish (Danio rerio) are useful organisms to study these biomineralized crystals called otoliths, as many required genes...
7.
Barta C, Liu H, Chen L, Giffen K, Li Y, Kramer K, et al.
Sci Data . 2018 Feb; 5:180005. PMID: 29406519
Although hair cells are the sensory receptors of the auditory and vestibular systems in the ears of all vertebrates, hair cell properties are different between non-mammalian vertebrates and mammals. To...
8.
Galanternik M, Kramer K, Piotrowski T
Cell Rep . 2015 Jan; 10(3):414-428. PMID: 25600875
Collective cell migration is a highly regulated morphogenetic movement during embryonic development and cancer invasion that involves the precise orchestration and integration of cell-autonomous mechanisms and environmental signals. Coordinated lateral...
9.
Lundberg Y, Xu Y, Thiessen K, Kramer K
Dev Dyn . 2014 Sep; 244(3):239-53. PMID: 25255879
Background: Otoconia are bio-crystals that couple mechanic forces to the sensory hair cells in the utricle and saccule, a process essential for us to sense linear acceleration and gravity for...
10.
Gorsi B, Liu F, Ma X, Chico T, V A, Kramer K, et al.
Angiogenesis . 2013 Aug; 17(1):77-91. PMID: 23959107
Arterial and venous specification is critical for establishing and maintaining a functioning vascular system, and defects in key arteriovenous signaling pathways including VEGF (vascular endothelial growth factor) lead to congenital...