Kenneth Kak-Yuen Wong
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Explore the profile of Kenneth Kak-Yuen Wong including associated specialties, affiliations and a list of published articles.
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39
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1463
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Recent Articles
21.
Zhou J, Chu H, Li C, Wong B, Cheng Z, Poon V, et al.
J Infect Dis
. 2013 Sep;
209(9):1331-42.
PMID: 24065148
Middle East respiratory syndrome coronavirus (MERS-CoV) infection caused severe pneumonia and multiorgan dysfunction and had a higher crude fatality rate (around 50% vs. 10%) than SARS coronavirus (SARS-CoV) infection. To...
22.
Cheng G, Tang C, Wong E, Cheng W, So M, Miao X, et al.
J Hepatol
. 2013 Jul;
59(6):1285-91.
PMID: 23872602
Background & Aims: Biliary atresia (BA) is a rare and most severe cholestatic disease in neonates, but the pathogenic mechanisms are unknown. Through a previous genome wide association study (GWAS)...
23.
Wong E, Cui L, Ng C, Tang C, Liu X, So M, et al.
Hum Mol Genet
. 2012 Oct;
22(3):621-31.
PMID: 23108157
Anorectal malformations (ARMs, congenital obstruction of the anal opening) are among the most common birth defects requiring surgical treatment (2-5/10 000 live-births) and carry significant chronic morbidity. ARMs present either...
24.
Tang C, Cheng G, So M, Yip B, Miao X, Wong E, et al.
PLoS Genet
. 2012 May;
8(5):e1002687.
PMID: 22589734
Hirschsprung disease (HSCR) is a congenital disorder characterized by aganglionosis of the distal intestine. To assess the contribution of copy number variants (CNVs) to HSCR, we analysed the data generated...
25.
So M, Leon T, Cheng G, Tang C, Miao X, Cornes B, et al.
PLoS One
. 2011 Dec;
6(12):e28986.
PMID: 22174939
Rare (RVs) and common variants of the RET gene contribute to Hirschsprung disease (HSCR; congenital aganglionosis). While RET common variants are strongly associated with the commonest manifestation of the disease...
26.
Ngan E, Garcia-Barcelo M, Yip B, Poon H, Lau S, Kwok C, et al.
J Clin Invest
. 2011 Aug;
121(9):3467-78.
PMID: 21841314
Hirschsprung (HSCR) disease is a complex genetic disorder attributed to a failure of the enteric neural crest cells (ENCCs) to form ganglia in the hindgut. Hedgehog and Notch are implicated...
27.
Tang C, Ngan E, Tang W, So M, Cheng G, Miao X, et al.
Hum Genet
. 2011 Jun;
131(1):67-76.
PMID: 21706185
Hirschsprung disease (HSCR, congenital colon aganglionosis) is a relatively common complex genetic condition caused by abnormal development of the enteric nervous system (ENS). Through a recent genome-wide association study conducted...
28.
Tang C, Tang W, So M, Miao X, Leung B, Yip B, et al.
PLoS One
. 2011 Feb;
6(1):e16181.
PMID: 21283760
The primary pathology of Hirschsprung's disease (HSCR, colon aganglionosis) is the absence of ganglia in variable lengths of the hindgut, resulting in functional obstruction. HSCR is attributed to a failure...
29.
Garcia-Barcelo M, Yeung M, Miao X, Tang C, Cheng G, Chen G, et al.
Hum Mol Genet
. 2010 May;
19(14):2917-25.
PMID: 20460270
Biliary atresia (BA) is characterized by the progressive fibrosclerosing obliteration of the extrahepatic biliary system during the first few weeks of life. Despite early diagnosis and prompt surgical intervention, the...
30.
Miao X, Garcia-Barcelo M, So M, Tang W, Dong X, Wang B, et al.
J Pediatr Surg
. 2010 Apr;
45(4):709-13.
PMID: 20385275
Background: Infantile hypertrophic pyloric stenosis (IHPS) is one of the most common gastrointestinal obstructions in the infancy requiring surgery. Reduced expression of neuronal nitric oxide synthase (nNOS), which plays an...