Kenneth C Hess
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Explore the profile of Kenneth C Hess including associated specialties, affiliations and a list of published articles.
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9
Citations
499
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Recent Articles
1.
Hess K, Liu J, Manfredi G, Muhlschlegel F, Buck J, Levin L, et al.
FASEB J
. 2014 Jul;
28(10):4369-80.
PMID: 25002117
Mitochondria, the major source of cellular energy in the form of ATP, respond to changes in substrate availability and bioenergetic demands by employing rapid, short-term, metabolic adaptation mechanisms, such as...
2.
Zippin J, Chen Y, Straub S, Hess K, Diaz A, Lee D, et al.
J Biol Chem
. 2013 Oct;
288(46):33283-91.
PMID: 24100033
The second messenger molecule cAMP is integral for many physiological processes. In mammalian cells, cAMP can be generated from hormone- and G protein-regulated transmembrane adenylyl cyclases or via the widely...
3.
Salazar E, Bank E, Ramsey N, Hess K, Deitsch K, Levin L, et al.
PLoS One
. 2012 Jul;
7(6):e39769.
PMID: 22761895
The most severe form of human malaria is caused by the parasite Plasmodium falciparum. The second messenger cAMP has been shown to be important for the parasite's ability to infect...
4.
Ramos-Espiritu L, Hess K, Buck J, Levin L
J Pharmacol Exp Ther
. 2011 Jun;
338(3):925-31.
PMID: 21665942
In addition to increasing cGMP, the soluble guanylyl cyclase (sGC) activator 3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole (YC-1) can elevate intracellular cAMP levels. This response was assumed to be as a result of cGMP-dependent inhibition...
5.
Townsend P, Holliday P, Fenyk S, Hess K, Gray M, Hodgson D, et al.
J Biol Chem
. 2008 Nov;
284(2):784-91.
PMID: 19008230
Carbon dioxide is fundamental to the physiology of all organisms. There is considerable interest in the precise molecular mechanisms that organisms use to directly sense CO(2). Here we demonstrate that...
6.
Stessin A, Zippin J, Kamenetsky M, Hess K, Buck J, Levin L
J Biol Chem
. 2006 Apr;
281(25):17253-17258.
PMID: 16627466
Nerve growth factor (NGF) and the ubiquitous second messenger cyclic AMP (cAMP) are both implicated in neuronal differentiation. Multiple studies indicate that NGF signals to at least a subset of...
7.
Hess K, Jones B, Marquez B, Chen Y, Ord T, Kamenetsky M, et al.
Dev Cell
. 2005 Aug;
9(2):249-59.
PMID: 16054031
Mammalian fertilization is dependent upon a series of bicarbonate-induced, cAMP-dependent processes sperm undergo as they "capacitate," i.e., acquire the ability to fertilize eggs. Male mice lacking the bicarbonate- and calcium-responsive...
8.
Steegborn C, Litvin T, Hess K, Capper A, Taussig R, Buck J, et al.
J Biol Chem
. 2005 Jul;
280(36):31754-9.
PMID: 16002394
Catechol estrogens are steroid metabolites that elicit physiological responses through binding to a variety of cellular targets. We show here that catechol estrogens directly inhibit soluble adenylyl cyclases and the...
9.
Zippin J, Farrell J, Huron D, Kamenetsky M, Hess K, Fischman D, et al.
J Cell Biol
. 2004 Feb;
164(4):527-34.
PMID: 14769862
Bicarbonate-responsive "soluble" adenylyl cyclase resides, in part, inside the mammalian cell nucleus where it stimulates the activity of nuclear protein kinase A to phosphorylate the cAMP response element binding protein...