Ken R Bracke
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Explore the profile of Ken R Bracke including associated specialties, affiliations and a list of published articles.
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Articles
97
Citations
3460
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Recent Articles
1.
Bracke K
Am J Respir Crit Care Med
. 2024 May;
210(8):969-971.
PMID: 38760002
No abstract available.
2.
Bogaert B, Debisschop A, Ehouarne T, Van Eeckhoutte H, De Volder J, Jacobs A, et al.
Nano Lett
. 2024 Mar;
24(10):2961-2971.
PMID: 38477058
The delivery of RNA across biological barriers can be achieved by encapsulation in lipid nanoparticles (LNPs). Cationic amphiphilic drugs (CADs) are pharmacologically diverse compounds with ionizable lipid-like features. In this...
3.
Merckx P, Conickx G, Blomme E, Maes T, Bracke K, Brusselle G, et al.
Eur J Pharm Biopharm
. 2024 Feb;
197:114223.
PMID: 38367760
The lung is an attractive target organ for inhalation of RNA therapeutics, such as small interfering RNA (siRNA). However, clinical translation of siRNA drugs for application in the lung is...
4.
Liu G, Haw T, Starkey M, Philp A, Pavlidis S, Nalkurthi C, et al.
Nat Commun
. 2023 Nov;
14(1):7349.
PMID: 37963864
Toll-like receptor 7 (TLR7) is known for eliciting immunity against single-stranded RNA viruses, and is increased in both human and cigarette smoke (CS)-induced, experimental chronic obstructive pulmonary disease (COPD). Here...
5.
De Paepe B, Bracke K, De Bleecker J
Brain Sci
. 2023 Oct;
13(10).
PMID: 37891738
The implementation of novel blood-based biomarkers is desired to reduce the diagnostic delay and burden for myositis patients. In this retrospective study, the potential of C-X-C motif chemokine ligand 10...
6.
7.
Goeteyn E, Grassi L, Van den Bossche S, Rigauts C, Vande Weygaerde Y, Van Braeckel E, et al.
Front Immunol
. 2023 May;
14:1176044.
PMID: 37168857
Patients with chronic lung disease suffer from persistent inflammation and are typically colonized by pro-inflammatory pathogenic bacteria. Besides these pathogens, a wide variety of commensal species is present in the...
8.
Van Eeckhoutte H, Donovan C, Kim R, Conlon T, Ansari M, Khan H, et al.
Eur Respir J
. 2022 Dec;
61(4).
PMID: 36549711
Background: Receptor-interacting protein kinase 1 (RIPK1) is a key mediator of regulated cell death (including apoptosis and necroptosis) and inflammation, both drivers of COPD pathogenesis. We aimed to define the...
9.
Van Cleemput J, van Snippenberg W, Lambrechts L, Dendooven A, DOnofrio V, Couck L, et al.
Nat Commun
. 2022 Oct;
13(1):6247.
PMID: 36271014
No abstract available.
10.
Jacobs M, Verschraegen S, Salhi B, Anckaert J, Mestdagh P, Brusselle G, et al.
Respir Res
. 2022 Oct;
23(1):287.
PMID: 36253785
Background: Two opposing B cell subsets have been defined based on their cytokine profile: IL-6 producing effector B cells (B-effs) versus IL-10 producing regulatory B cells (B-regs) that respectively positively...