Kelvin Carrasquillo-Carrion
Overview
Explore the profile of Kelvin Carrasquillo-Carrion including associated specialties, affiliations and a list of published articles.
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14
Citations
45
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Recent Articles
1.
Monero-Paredes M, Santiago E, Carrasquillo-Carrion K, Renta J, Rogozin I, Roche-Lima A, et al.
Int J Mol Sci
. 2024 Oct;
25(19).
PMID: 39408985
Clopidogrel, a prescription drug to reduce ischemic events in cardiovascular patients, has been extensively studied in mostly European individuals but not among Caribbean Hispanics. This study evaluated the low abundance...
2.
Velez-Lopez O, Carrasquillo-Carrion K, Cantres-Rosario Y, Machin-Martinez E, Alvarez-Rios M, Roche-Lima A, et al.
Biomedicines
. 2024 Sep;
12(9).
PMID: 39335448
HIV-1 infects monocyte-derived macrophages (MDM) that migrate into the brain and secrete virus and neurotoxic molecules, including cathepsin B (CATB), causing cognitive dysfunction. Cocaine potentiates CATB secretion and neurotoxicity in...
3.
Rosario-Rodriguez L, Cantres-Rosario Y, Carrasquillo-Carrion K, Rosa-Diaz A, Rodriguez-De Jesus A, Rivera-Nieves V, et al.
Int J Mol Sci
. 2024 May;
25(10).
PMID: 38791465
Viral strains, age, and host factors are associated with variable immune responses against SARS-CoV-2 and disease severity. Puerto Ricans have a genetic mixture of races: European, African, and Native American....
4.
Rosario-Rodriguez L, Cantres-Rosario Y, Carrasquillo-Carrion K, Rodriguez-De Jesus A, Cartagena-Isern L, Garcia-Requena L, et al.
Int J Mol Sci
. 2024 Mar;
25(6).
PMID: 38542221
HIV-associated neurocognitive disorders (HAND) affect 15-55% of HIV-positive patients and effective therapies are unavailable. HIV-infected monocyte-derived macrophages (MDM) invade the brain of these individuals, promoting neurotoxicity. We demonstrated an increased...
5.
Roche-Lima A, Rosado-Quinones A, Feliu-Maldonado R, Figueroa-Gispert M, Diaz-Rivera J, Diaz-Gonzalez R, et al.
Acta Parasitol
. 2024 Jan;
69(1):415-425.
PMID: 38165555
Purpose: Antimalarial drug resistance is a global public health problem that leads to treatment failure. Synergistic drug combinations can improve treatment outcomes and delay the development of drug resistance. Here,...
6.
Monero-Paredes M, Feliu-Maldonado R, Carrasquillo-Carrion K, Gonzalez P, Rogozin I, Roche-Lima A, et al.
Genes (Basel)
. 2023 Sep;
14(9).
PMID: 37761953
Cardiovascular disease (CVD) is one of the leading causes of death in Puerto Rico, where clopidogrel is commonly prescribed to prevent ischemic events. Genetic contributors to both a poor clopidogrel...
7.
Borges-Velez G, Rosado-Philippi J, Cantres-Rosario Y, Carrasquillo-Carrion K, Roche-Lima A, Perez-Vargas J, et al.
J Mol Histol
. 2021 Jul;
53(2):199-214.
PMID: 34264436
Zika virus (ZIKV) infection has been associated with fetal abnormalities by compromising placental integrity, but the mechanisms by which this occurs are unknown. Flavivirus can deregulate the host proteome, especially...
8.
Rogozin I, Roche-Lima A, Tyryshkin K, Carrasquillo-Carrion K, Lada A, Poliakov L, et al.
Front Genet
. 2021 Jun;
12:671866.
PMID: 34093666
Cancer genomes harbor numerous genomic alterations and many cancers accumulate thousands of nucleotide sequence variations. A prominent fraction of these mutations arises as a consequence of the off-target activity of...
9.
Martinez-Matias N, Chorna N, Gonzalez-Crespo S, Villanueva L, Montes-Rodriguez I, Melendez-Aponte L, et al.
Sci Rep
. 2021 Apr;
11(1):7411.
PMID: 33795741
Functional analysis of the Mtl1 protein in Saccharomyces cerevisiae has revealed that this transmembrane sensor endows yeast cells with resistance to oxidative stress through a signaling mechanism called the cell...
10.
Roche-Lima A, Roman-Santiago A, Feliu-Maldonado R, Rodriguez-Maldonado J, Nieves-Rodriguez B, Carrasquillo-Carrion K, et al.
Front Pharmacol
. 2020 Feb;
10:1550.
PMID: 32038238
Despite some previous examples of successful application to the field of pharmacogenomics, the utility of machine learning (ML) techniques for warfarin dose predictions in Caribbean Hispanic patients has yet to...