Kelsey B Bennion
Overview
Explore the profile of Kelsey B Bennion including associated specialties, affiliations and a list of published articles.
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5
Citations
40
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Recent Articles
1.
Bennion K, Liu D, Dawood A, Wyatt M, Alexander K, Abdel-Hakeem M, et al.
Nat Commun
. 2024 Jun;
15(1):5280.
PMID: 38902261
The regulatory circuits dictating CD8 T cell responsiveness versus exhaustion during anti-tumor immunity are incompletely understood. Here we report that tumor-infiltrating antigen-specific PD-1 TCF-1 CD8 T cells express the immunosuppressive...
2.
Bennion K, Tariq M, Wyatt M, Duneton C, Baecher K, Paulos C, et al.
Sci Transl Med
. 2023 Aug;
15(710):eadd1868.
PMID: 37611081
Checkpoint inhibition using Fc-containing monoclonal antibodies has emerged as a powerful therapeutic approach to augment antitumor immunity. We recently showed that FcγRIIB, the only inhibitory IgG-Fc receptor, is expressed on...
3.
Chen C, Bennion K, Swift D, Morrow K, Zhang W, Oami T, et al.
J Immunol
. 2021 Apr;
206(10):2412-2419.
PMID: 33911005
Sepsis induces significant immune dysregulation characterized by lymphocyte apoptosis and alterations in the cytokine milieu. Because cancer patients exhibit a 10-fold greater risk of developing sepsis compared with the general...
4.
Townsend M, Bennion K, Bitter E, Felsted A, Robison R, ONeill K
Exp Cell Res
. 2021 Apr;
403(1):112567.
PMID: 33812866
We chose to evaluate Hypoxanthine Guanine Phosphoribosyltransferase (HPRT) as a possible biomarker for prostate cancer due to its involvement in nucleotide synthesis and cell cycle progression. We utilized two prostate...
5.
Farley C, Morris A, Tariq M, Bennion K, Potdar S, Kudchadkar R, et al.
JCI Insight
. 2021 Feb;
6(4).
PMID: 33616086
In the setting of cancer, T cells upregulate coinhibitory molecules that attenuate TCR signaling and lead to the loss of proliferative capacity and effector function. Checkpoint inhibitors currently in clinical...