Kelly T Hughes
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Explore the profile of Kelly T Hughes including associated specialties, affiliations and a list of published articles.
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91
Citations
3175
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Recent Articles
11.
Plitnick J, Chevance F, Stringer A, Hughes K, Wade J
J Bacteriol
. 2020 Dec;
203(4).
PMID: 33257526
FliA is a broadly conserved σ factor that directs transcription of genes involved in flagellar motility. We previously identified FliA-transcribed genes in and serovar Typhimurium, and we showed that FliA...
12.
Akhade A, Atif S, Lakshmi B, Dikshit N, Hughes K, Qadri A, et al.
Proc Natl Acad Sci U S A
. 2020 Nov;
117(47):29811-29822.
PMID: 33177235
Inflammasomes have been implicated in the detection and clearance of a variety of bacterial pathogens, but little is known about whether this innate sensing mechanism has any regulatory effect on...
13.
Education and communication are critical to effectively incorporating cannabis into cancer treatment
Hughes K, Casarett D
Cancer
. 2020 Sep;
127(1):27-30.
PMID: 32986251
No abstract available.
14.
Wozniak C, Hendriksen J, Olivera B, Roth J, Hughes K
J Bacteriol
. 2020 Aug;
202(20).
PMID: 32747428
A mutant of serovar Typhimurium was isolated that simultaneously affected two metabolic pathways as follows: NAD metabolism and DNA repair. The mutant was isolated as resistant to a nicotinamide analog...
15.
Horstmann J, Lunelli M, Cazzola H, Heidemann J, Kuhne C, Steffen P, et al.
Nat Commun
. 2020 Apr;
11(1):2013.
PMID: 32332720
The long external filament of bacterial flagella is composed of several thousand copies of a single protein, flagellin. Here, we explore the role played by lysine methylation of flagellin in...
16.
Wozniak C, Lin Z, Schmidt E, Hughes K, Liou T
Antimicrob Agents Chemother
. 2018 Jun;
62(9).
PMID: 29914944
Microbes encode many uncharacterized gene clusters that may produce antibiotics and other bioactive small molecules. Methods for activating these genes are needed to explore their biosynthetic potential. A transposon containing...
17.
Asmar A, Ferreira J, Cohen E, Cho S, Beeby M, Hughes K, et al.
PLoS Biol
. 2017 Dec;
15(12):e2004303.
PMID: 29257832
The cell envelope of gram-negative bacteria, a structure comprising an outer (OM) and an inner (IM) membrane, is essential for life. The OM and the IM are separated by the...
18.
Hughes K, Chevance F
RNA Biol
. 2017 Nov;
15(2):182-185.
PMID: 29130371
A complex process translates messenger RNA (mRNA) base sequence into protein amino acid sequence. Transfer RNAs must recognize 3-base codons in the mRNA to insert the correct amino acids into...
19.
Ward E, Renault T, Kim E, Erhardt M, Hughes K, Blair D
Mol Microbiol
. 2017 Oct;
107(1):94-103.
PMID: 29076571
During assembly of the bacterial flagellum, protein subunits that form the exterior structures are exported through a specialized secretion apparatus energized by the proton gradient. This category of protein transport,...
20.